Systemic isotretinoin treatment and pregnancy: A comparative study of two groups of women: A retrospective analysis of 569 women

• DOI: 10.7241/ourd.2017.10.2017
• Publication Date: 2023-10-10T17:24:57Z
• Authors: Piotr Brzezinski; Borowska Katarzyna; Chiriac Anca; Smigielski Janusz
• Keywords: Isotretinoin

Background: Oral isotretinoin is the only drug which promotes prolonged remission or cure of severe acne. The aim our study was to estimate exposure and evaluate effectiveness Polish Romanian pregnancy prevention. This a comparative two groups women. Methods: A retrospective, 569 women with acne vulgaris. included randomly selected during treatment follow-up. Group I rigorous prevention pregnancy; II without this rigor. Results: We did not register any pregnancies. 1.93% used oral contraceptives, 92.79% condom sex, 7.21% abstained from sex. analysis showed significant differences (p <0.0001) total dose applied depending on method treatment. No statistically correlations were found between patients' age, duration disease, location, type Average length therapy 8.81 months. Isotretinoin interrupted for 27 patients group I. Conclusion: in Poland Romania very good study. Every woman fertile phase life should use contraception while taking isotretinoin. most important thing awareness patient.