Hemorrhagic Stroke Probably Caused by Exercise Combined With a Sports Supplement Containing β-Methylphenyl-ethylamine (BMPEA): A Case Report

• DOI: 10.7326/l15-0106
• Publication Date: 2015-05-11T22:30:50Z
• Authors: Pieter A. Cohen; Rickard Zeijlon; Rachel Nardin; Peter H.J. Keizers; Bastiaan Venhuis
• Keywords: 03 medical and health sciences; 0302 clinical medicine; 610

Letters16 June 2015Hemorrhagic Stroke Probably Caused by Exercise Combined With a Sports Supplement Containing β-Methylphenyl-ethylamine (BMPEA): A Case ReportPieter A. Cohen, MD, Rickard Zeijlon, Rachel Nardin, Peter H.J. Keizers, PhD, and Bastiaan Venhuis, PhDPieter MDFrom Harvard Medical School, Boston, Massachusetts; Sahlgrenska University Hospital, Gothenburg, Sweden; National Institute for Public Health the Environment (RIVM), Bilthoven, Netherlands., PhDFrom Netherlands.Author, Article, Disclosure Informationhttps://doi.org/10.7326/L15-0106 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Background: The U.S. Food Drug Administration has warned consumers that an isomer of amphetamine, β-methylphenylethylamine (BMPEA), is found in many sports supplements (1). health effects this chemical humans are unknown (2, 3).Objective: To report case hemorrhagic stroke probably caused exercise combined with BMPEA.Case Report: 53-year-old woman presented 1 day numbness clumsiness her left hand. She reported sudden onset symptoms 45 minutes after beginning vigorous routine she had repeated several times weekly few years.On examination, was afebrile, blood ...References1. Administration. BMPEA dietary supplements. 24 April 2015. Accessed at www.fda.gov/food/dietarysupplements/qadietarysupplements/ucm443790.htm on 28 Google Scholar2. Pawar RS, Grundel E, Fardin-Kia AR, Rader JI. Determination selected biogenic amines Acacia rigidula plant materials using LC-MS/MS methods. J Pharm Biomed Anal. 2014;88:457-66. [PMID: 24176750] doi:10.1016/j.jpba.2013.09.012 CrossrefMedlineGoogle Scholar3. Cohen PA, Bloszies C, Yee Gerona R. An amphetamine whose efficacy safety never been studied, multiple Test 25847603] doi:10.1002/dta.1793 Scholar4. Zeijlon R, Andersson B. Hjärnblödning efter intag av prestationshöjaren "Jacked Power." Frisk kvinna insjuknade under träning en enda dos. Läkartidningen. 2014;111:1782-4. 25699325] MedlineGoogle Scholar5. Edwards IR, Aronson JK. Adverse drug reactions: definitions, diagnosis, management. Lancet. 2000;356:1255-9. 11072960] Scholar Author, InformationAffiliations: From Netherlands.Disclosures: Authors have disclosed no conflicts interest. Forms can be viewed www.acponline.org/authors/icmje/ConflictOf InterestForms.do?msNum=L15-0106.This article published online first www.annals.org 12 May PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByA content analysis marketing packages weight loss muscle buildingNine prohibited stimulants supplements: deterenol, phenpromethamine (Vonedrine), oxilofrine, octodrine, beta-methylphenylethylamine 1,3-dimethylamylamine (1,3-DMAA), 1,4-dimethylamylamine (1,4-DMAA), 1,3-dimethylbutylamine (1,3-DMBA) higenamineHPLC-UV-QDa Citrus aurantium-labelled pre-workout suggest only minority contain extractPRE-WORKOUT SUPPLEMENT INDUCED CARDIAC ISCHAEMIA IN YOUNG FEMALEKratom Adulterated Phenylethylamine Associated Intracerebral Hemorrhage: Linking Toxicologists Officials Identify Dangerous AdulterantsThe Adulterant β -Methylphenethylamine Increases Blood Pressure Acting Peripheral Norepinephrine TransportersFora fuelling discovery fortified – exploratory study directed monitoring internet contaminated food based their usersFour experimental 2-amino-6-methylheptane (octodrine), (1,3-DMAA) (1,3-DMBA)Overview regulation USA issues adulteration phenethylamines (PEAs)Banned discouraged-use ingredients supplementsEmergency department visits hospitalisations adverse events related commonHistory full circle: 'Novel' sympathomimetics supplementsProtecting military personnel from high risk supplementsBreaking gridlock: Regulation United States 16 2015Volume 162, Issue 12Page: 879-880KeywordsAdverse reactionsAmphetaminesBlood pressureDrug administrationDrugsExerciseHemorrhageHemorrhagic strokeSports ePublished: 2015 Published: CopyrightCopyright © American College Physicians. All Rights Reserved.PDF DownloadLoading ...