P014: Improving early HIV diagnosis by increasing HIV testing: experience in León, Guanajuato, Mexico

• DOI: 10.7448/ias.18.3.20145
• Publication Date: 2015-04-16T08:25:31Z
• Authors: Juan Luis Mosqueda; Ericka Magdalena ...; José Álvarez; Santiago Ignacio ...; Emilio Francisco ...
• Keywords: HIV diagnosis

Antiretroviral therapies have proved life-saving in HIV infection, dramatically reducing morbidity and mortality.With longer survival, morbidities mortalities infection are increasingly similar to the associated with ageing.In treated risk of these is linked immune activation, inflammation coagulation indices.And persons failure restore circulating CD4 T cell numbers a greater as well heightened levels coagulation.The drivers incompletely defined could be related sustained low viral replication tissues, translocation microbial products across damaged gut mucosa, co-pathogens such cytomegalovirus, increased inflammatory lipids, or homeostatic responses lymphocytopenia that may drive expansion CD8 numbers.We present here models link morbid outcomes pathogenesis restoration expansion.