P015: HIV-1 subtype distribution and circulating recombinant forms in Colombia 2011–2014

• DOI: 10.7448/ias.18.3.20146
• Publication Date: 2015-04-16T08:25:31Z
• Authors: Andres Gonzalez; Daniel Escobar; Jenny Andrea Carmona; Juan Carlos Gonzalez
• Keywords: 03 medical and health sciences; 0302 clinical medicine

Antiretroviral therapies have proved life-saving in HIV infection, dramatically reducing morbidity and mortality.With longer survival, morbidities mortalities infection are increasingly similar to the associated with ageing.In treated risk of these is linked immune activation, inflammation coagulation indices.And persons failure restore circulating CD4 T cell numbers a greater as well heightened levels coagulation.The drivers incompletely defined could be related sustained low viral replication tissues, translocation microbial products across damaged gut mucosa, co-pathogens such cytomegalovirus, increased inflammatory lipids, or homeostatic responses lymphocytopenia that may drive expansion CD8 numbers.We present here models link morbid outcomes pathogenesis restoration expansion.