A diversity of localized timescales in network activity

• DOI: 10.7554/elife.01239
• Publication Date: 2014-01-21T16:18:17Z
• Authors: Rishidev Chaudhuri; Alberto Bernacchia; Xiao-Jing Wang
• Keywords: Network Dynamics; Nerve net; Dynamics; Network Analysis

Neurons show diverse timescales, so that different parts of a network respond with disparate temporal dynamics. Such diversity is observed both when comparing timescales across brain areas and among cells within local populations; the underlying circuit mechanism remains unknown. We examine conditions under which spatially connectivity can produce such behavior. In linear network, are segregated if eigenvectors matrix localized to network. develop framework predict shapes eigenvectors. Notably, alone insufficient for separate timescales. However, localization be realized by heterogeneity in profile, we demonstrate two classes architecture allow localization. Our results suggest relate structural functional and, beyond neural dynamics, generally applicable relationship between structure dynamics biological networks.