Innate lymphoid cells and COVID-19 severity in SARS-CoV-2 infection

• DOI: 10.7554/elife.74681
• Publication Date: 2022-03-11T13:00:28Z
• Authors: Noah J Silverstein; Yetao Wang; Zachary Manickas-...; Claudia Carbone; Ann Dauphin; Brittany P Boribong; Maggie Loiselle; Jameson Davis; Maureen M Leonard; Leticia Kuri-Cerv...; ; Nuala J Meyer; Michael R Betts; Jonathan Z Li; Bruce D Walker; Xu G Yu; Lael M Yonker; Jeremy Luban
• Keywords: 2019-20 coronavirus outbreak; Betacoronavirus; Innate lymphoid cell

Risk of severe COVID-19 increases with age, is greater in males, and associated lymphopenia, but not higher burden SARS-CoV-2. It unknown whether effects age sex on abundance specific lymphoid subsets explain these correlations.