A single-cell atlas of the cycling murine ovary
Ovulation
0301 basic medicine
0303 health sciences
QH301-705.5
estrous cycle
Science
Q
Ovary
R
Estrous Cycle
single-cell RNA sequencing
Pelvis
Mice
03 medical and health sciences
Ovarian Follicle
Medicine
Animals
ovary
Female
Biology (General)
mouse
Developmental Biology
DOI:
10.7554/elife.77239
Publication Date:
2022-10-07T12:01:40Z
AUTHORS (13)
ABSTRACT
The estrous cycle is regulated by rhythmic endocrine interactions of the nervous and reproductive systems, which coordinate hormonal ovulatory functions ovary. Folliculogenesis follicle progression require orchestrated response a variety cell types to allow maturation its sequela, ovulation, corpus luteum formation, wound repair. Little known about state dynamics ovary during paracrine factors that help this process. Herein, we used single-cell RNA sequencing evaluate transcriptome >34,000 cells adult mouse describe transcriptional changes occur across normal other states build comprehensive dynamic atlas murine ovarian states.
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CITATIONS (58)
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