Manganese-enhanced magnetic resonance imaging reveals light-induced brain asymmetry in embryo

0301 basic medicine Manganese Gallus gallus domesticus; MEMRI; brain; chicken; embryonic development; lateralization; neuroscience QH301-705.5 brain Science Q R MEMRI Brain Embryo, Mammalian Magnetic Resonance Imaging 3. Good health Gallus gallus domesticus 03 medical and health sciences 0302 clinical medicine embryonic development lateralization Medicine Animals Biology (General) Chickens Neuroscience
DOI: 10.7554/elife.86116 Publication Date: 2023-09-05T13:20:11Z
ABSTRACT
The idea that sensory stimulation to the embryo (in utero or in ovo) may be crucial for brain development is widespread. Unfortunately, up to now evidence was only indirect because mapping of embryonic brain activity in vivo is challenging. Here, we applied for the first time manganese enhanced magnetic resonance imaging (MEMRI), a functional imaging method, to the eggs of domestic chicks. We revealed light-induced brain asymmetry by comparing embryonic brain activity in vivo of eggs that were stimulated by light or maintained in the darkness. Our protocol paves the way to investigation of the effects of a variety of sensory stimulations on brain activity in embryo.
SUPPLEMENTAL MATERIAL
Coming soon ....
REFERENCES (13)
CITATIONS (8)
EXTERNAL LINKS
PlumX Metrics
RECOMMENDATIONS
FAIR ASSESSMENT
Coming soon ....
JUPYTER LAB
Coming soon ....