Neural Correlates and Reinstatement of Recent and Remote Memory: A Comparison Between Children and Young Adults

• DOI: 10.7554/elife.89908.2
• Publication Date: 2024-07-18T12:25:20Z
• Authors: Iryna Schommartz; Philip F Lembcke; Javier Ortiz-Tudela; Martin Bauer; Angela M Kaindl; Claudia Buss; Yee Lee Shing
• Keywords: Parahippocampal gyrus

Children showed less robust memory consolidation across short and long delay compared to young adults.From delay, children show differential neural upregulation for remote versus recent adults.Over time, both adults reduced scene-specific reinstatement of patterns.Children relied more on gist-like in anterior hippocampal medial prefrontal brain regions.Memory tends be childhood than adulthood. However, little is known about the corresponding functional differences developing that may underlie age-related retention memories over time. This study examined system-level object-scene associations after learning (immediate delay), one night sleep (short as well two weeks (long delay) 5-to-7-year-old (n = 49) 39), a reference group with mature systems. Particularly, we characterized how activation patterns change assessed by magnetic resonance imaging combined representational similarity analysis (RSA). Our results was strong (i.e., forgetting) adults. Contrasting correctly retained time posterior parahippocampal gyrus, lateral occipital cortex, cerebellum In addition, decrease indicating time-related decay detailed differentiated memories. At same observed generic medial-temporal regions uniquely children, qualitative difference trace children. Taken together, adults, consolidation, possibly due difficulties engaging neocortical mnemonic during retrieval memories, coupled relying reinstatement.