Gut microbiota in hospitalized children with acute infective gastroenteritis caused by virus or bacteria in a regional Peruvian hospital

• DOI: 10.7717/peerj.9964
• Publication Date: 2020-11-03T10:30:42Z
• Authors: Andre Alonso Taco...; Augusto R. Fernan...; Angela Cornejo-Tapia; Miguel Angel Agui...; Luis J. del Valle; Wilmer Silva-Caso; Victor Zavaleta-G...; Pablo Weilg; Hernán Cornejo-Pa...; Jorge Bazán-Mayra; Zully M. Puyen; Juana del Valle-M...
• Keywords: Prevotella; Etiology

Acute infective gastroenteritis (AIG) is a leading cause of mortality in children worldwide. In Peru, more than 40% cases AIG occurring under 5 years old. The disruption the gut microbiota can increase risk for several health complications especially patients with gastric infections caused by viruses or bacteria.The main objective this study was to describe prevalence 13 representative bacteria from (GM) stools samples age acute gastroenteritis.The most commonly isolated GM were Firmicutes (63.2% 74/117) Bacteriodetes (62.4%; 73/117), Lactobacillus (59.8%; 70/117), Prevotella (57.2%; 67/117), Proteobacterium (53.8%; 63/117), regardless etiological agent responsible AIG. Interestingly, despite high Firmicutes, Bacteroidetes, and across all samples, visible reduction these agents observed among single bacterial infection even bacteria-bacteria coinfections when compared viral etiologies. Patients exclusive mixed breastfeeding registered highest amount bacteria, contrast infants who received formula not breastfed.