Prognostic Value of Serum β2-Microglobulin in Predicting Survival of Patients with Diffuse Large B-Cell Lymphoma

• DOI: 10.7754/clin.lab.2024.240907
• Publication Date: 2025-03-11T08:57:43Z
• Authors: Jun Zhong; Xiang Weng; Li Chen
• Keywords: Beta-2 microglobulin; Value (mathematics)

This study investigated the predictive value of β2-microglobulin (β2-MG) on prognosis diffuse large B-cell lymphoma (DLBCL) patients. Patients with DLBCL diagnosed by pathologic biopsy were collected from January 2021 through December 2022, and a total 98 patients finally included. The grouped according to their prognosis, i.e., into survival group (n = 69) death 29). critical β2-MG for in was obtained ROC curve. Kaplan Meier curve plotted analyze relationship between overall patients, one-way test performed examine clinical data Independent predictors affecting screened using unifactorial multifactorial Cox regression analysis. R 4.2.1 software used refit constructed column-line graph prediction model internal validation. 3.285 µg/L, All categorized following two groups: ≤ 75) > 23). During follow-up period, 9 endpoint events occurred 20 group. had higher rate than High levels β2-MG, LDH, CRP independent prognostic influences combined construct model, there better consistency predicted probability actual results. Poor treatment is closely related abnormally elevated β2-MG. are risk factors disease progression