Radical Prostatectomy and Pelvic Lymph Node Dissection in Kaiser Permanente Southern California: 15-Year Experience

• DOI: 10.7812/tpp/17-233
• Publication Date: 2019-01-24T21:47:33Z
• Authors: Pooya Banapour; Andrew Schumacher; Jane C Lin; David S Finley
• Keywords: Biochemical recurrence; Univariate analysis

Radical prostatectomy (RP) with pelvic lymph node dissection (PLND) is the standard treatment of high-risk prostate cancer. High-risk patients and those metastasis (LNM) require further treatment. We review outcomes RP+PLND in Kaiser Permanente Southern California (KPSC).Patients who underwent KPSC from January 1, 2001, to July 2015 were included. Patient charts retrospectively reviewed for demographic information clinicopathologic data which used calculate positive surgical margin rate, LNM, adjuvant treatment, 5-year biochemical recurrence, overall survival. Univariate multivariate logistic regression analyses identify factors associated positivity.Patients (N = 1829) (241 high-risk, 943 intermediate-risk, 645 low-risk). Positive rates 17.8%, 14.8%, 11.9% high, intermediate- low-risk groups. Biochemical recurrence 22% 12.1% category. Androgen deprivation use was 4.1% group 0.9% group. Five-year survival 92.5% node-positive 94.9% node-negative (p 0.8). On analysis, age (odds ratio [OR] 1.02, p 0.02), prebiopsy prostate-specific antigen (OR < 0.001), clinical T stage 1.49, 0.01) positivity.In KPSC, performed low-, intermediate-, Age, antigen, margins LNM. Recipients LNM required