Time-Intensity-Based Quantification of Vascularity With Single-Level Dynamic Contrast-Enhanced Ultrasonography

• DOI: 10.7863/jum.2005.24.7.975
• Publication Date: 2017-01-09T18:12:32Z
• Authors: Jie Li; Bao-wei Dong; Xiao-ling Yu; Xing-hua Wang; Chuan-fu Li
• Keywords: Mechanical index; Vascularity; Intensity; Parenchyma; Liver parenchyma; Bolus (digestion)

The purpose of this study was to delineate the hemodynamic features VX2 tumor and perineoplastic liver parenchyma evaluate potential usefulness single-level dynamic ultrasonography in diagnosis tumors by analysis time-intensity curves.An vivo animal model studied using a low mechanical index conjunction with contrast-enhanced ultrasonography. A sulfur hexafluoride contrast agent (SonoVue; Bracco SpA, Milan, Italy) applied 8 rabbits intravenous bolus injection. Data were acquired before after induction. Corresponding parameters curve measured wash-in/wash-out software.No significant difference found time enhancement, peak intensity, signal enhancement duration between induction (P > .05). typical pattern hyperechoic relative during early phase hypoechoic later phase. curves obtained carcinomas revealed an arrival intensity irregular sharp decrease very return baseline, presenting much more rapid wash-in wash-out ultrasonographic agents. There < .001).Single-level level could provide real-time continuous enhanced images fully tumors. may useful, complementary, quantitative information. This technique be useful for tumors, especially those showing atypical on biphasic helical computed tomographic scanning.