Sonographic Features of Triple-Negative and Non-Triple-Negative Breast Cancer

• DOI: 10.7863/jum.2012.31.10.1531
• Publication Date: 2017-01-09T18:50:47Z
• Authors: Sebastian Wojcinski; Amr A. Soliman; Julia Schmidt; Lars Makowski; Friedrich Degenhardt; Peter Hillemanns
• Keywords: Triple-negative breast cancer; Triple test

Triple-negative breast cancer (TNBC) is known to have unique molecular, clinical, and pathologic characteristics. The growth pattern of this may also affect its appearance on sonography. Our study evaluated the sonographic features TNBC according American College Radiology Breast Imaging Reporting Data System classification system compared these with those non-TNBC.Data from 315 consecutive cases were collected. images reevaluated by an examiner blinded patients' characteristics histologic results System. (n = 33) non-TNBC 282) compared.Triple-negative was significantly correlated a younger patient age (P .002) associated higher tumor grades < .001), more lymph node involvement .014), trend toward larger size. With regard features, margin frequently described as lobulated or microlobulated (75.8% versus 49.5% in non-TNBC; P .005). echoic halo observed less often than non-TNBC(39.4% 62.8%; .014). Cooper ligaments displaced rather disrupted .003). Regarding posterior acoustic enhancement (36.4% 13.0% .031).Triple-negative different features. This finding can be explained profile subtype. Some distinct criteria for are likely benign masses. Knowledge would help avoid false-negative type.