Optimization of Region of Interest Drawing for Quantitative Analysis

• DOI: 10.7863/ultra.14.10042
• Publication Date: 2015-10-22T12:56:23Z
• Authors: Norio Nakata; Tomoyuki Ohta; Makiko Nishioka; Hiroshi Takeyama; Yasuo Toriumi; Kumiko Kato; Hiroko Nogi; Makiko Kamio; Kunihiko Fukuda
• Keywords: Adult; Male; Observer Variation; Iron; Contrast Media; Reproducibility of Results; Breast Neoplasms; Oxides; Middle Aged; Image Enhancement; Ferric Compounds; Sensitivity and Specificity; Pattern Recognition, Automated; Diagnosis, Differential; 03 medical and health sciences; 0302 clinical medicine; Image Interpretation, Computer-Assisted; Humans; Female; Ultrasonography, Mammary; Algorithms; Aged

Objectives This study was performed to evaluate the diagnostic utility of quantitative analysis benign and malignant breast lesions using contrast‐enhanced sonography. Methods Contrast‐enhanced sonography perflubutane‐based contrast agent Sonazoid (Daiichi Sankyo, Tokyo, Japan) in 94 pathologically proven palpable mass lesions, which could be depicted with B‐mode Quantitative analyses time‐intensity curve on were 5 region interest (ROI) types (manually traced ROI circular ROIs 5, 10, 15, 20 mm diameter). The peak signal intensity, initial slope, time peak, positive enhancement integral, wash‐out ratio investigated each ROI. Results There significant differences between ( P < .05), slope .001), integral .05) for manual Significant found 5‐mm ROI; 10‐mm absolute values intensity .01), .005) 15‐mm 20‐mm no statistically any types. Conclusions Kinetic is useful differentiation lesions.