<i>Mycobacterium simiae</i>: a Possible Emerging Pathogen in Iran

• DOI: 10.7883/yoken.66.475
• Publication Date: 2015-06-17T18:02:40Z
• Authors: Abdolrazagh Hashe...; Davood Darban-Sar...; Parvin Heidarieh; Mohammad Mehdi Fe...; Shima Deshmir-Sal...; Sedigheh Khazaee; Seyed Mohammad Alavi
• Keywords: rpoB; Nontuberculous Mycobacteria

Mycobacterium simiae has been reported worldwide, particularly from the Middle East. This organism recognized as a causative agent of pulmonary and disseminated infections. In this study, we used molecular methods to detect patients who were suspected having tuberculosis. A total 117 isolates mycobacteria evaluated different regions Iran. Isolates identified using phenotypic gene sequencing 16S rRNA, rpoB, hsp65, ITS. Of isolates, 12 M. (10.2%) clinical samples, including bronchoalveolar lavage sputum (n = 8), blood 3), lymph node biopsy 1). Three (3/12, 25%) recovered samples HIV cases when CD4(+) count was less than 50/μl. There no significant relationship between infection age or gender. Infection with nontuberculous (NTM), simiae, is major problem among immunocompromised patients. The results study illustrated importance for accurate rapid detection NTM infections in treatment nonresponding