Cervical Priming Before Diagnostic Operative Hysteroscopy in Infertile Women: A Randomized, Double-Blind, Controlled Comparison of 2 Vaginal Misoprostol Doses
Adult
Dose-Response Relationship, Drug
Cervix Uteri
Hysteroscopy
Dilatation
Drug Administration Schedule
3. Good health
Cervical priming
Administration, Intravaginal
03 medical and health sciences
0302 clinical medicine
Office hysteroscopy
Double-Blind Method
Oxytocics
Premenopausal Women
Controlled-Trial
Outcome Assessment, Health Care
Preoperative Care
Humans
Female
Infertility, Female
Placebo
Misoprostol
DOI:
10.9738/intsurg-d-12-00024.1
Publication Date:
2013-05-23T14:58:28Z
AUTHORS (6)
ABSTRACT
The aim of this study was to evaluate the efficacy vaginal misoprostol for cervical priming at doses 200 mcg and 400 mcg, 12 15 hours before diagnostic office hysteroscopy (OH) without anesthesia in patients with infertility. Sixty infertile requiring a investigation infertility were included study. randomly allocated into 3 vaginally administered groups: (1) control group, (2) 200-mcg dose (3) 400-mcg group. Misoprostol significantly facilitated procedure OH: entry easier; procedural time shorter; baseline width larger; pain scoring lower groups compared Increasing from did not improve effect on dilation. is promising analog use OH. Since OH both have proven be effective regimens, may preferred. However, routine clinical usage, further research needed through large, randomized, controlled trials powered detect difference complications determine whether reduces
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