Cervical Priming Before Diagnostic Operative Hysteroscopy in Infertile Women: A Randomized, Double-Blind, Controlled Comparison of 2 Vaginal Misoprostol Doses

Adult Dose-Response Relationship, Drug Cervix Uteri Hysteroscopy Dilatation Drug Administration Schedule 3. Good health Cervical priming Administration, Intravaginal 03 medical and health sciences 0302 clinical medicine Office hysteroscopy Double-Blind Method Oxytocics Premenopausal Women Controlled-Trial Outcome Assessment, Health Care Preoperative Care Humans Female Infertility, Female Placebo Misoprostol
DOI: 10.9738/intsurg-d-12-00024.1 Publication Date: 2013-05-23T14:58:28Z
ABSTRACT
The aim of this study was to evaluate the efficacy vaginal misoprostol for cervical priming at doses 200 mcg and 400 mcg, 12 15 hours before diagnostic office hysteroscopy (OH) without anesthesia in patients with infertility. Sixty infertile requiring a investigation infertility were included study. randomly allocated into 3 vaginally administered groups: (1) control group, (2) 200-mcg dose (3) 400-mcg group. Misoprostol significantly facilitated procedure OH: entry easier; procedural time shorter; baseline width larger; pain scoring lower groups compared Increasing from did not improve effect on dilation. is promising analog use OH. Since OH both have proven be effective regimens, may preferred. However, routine clinical usage, further research needed through large, randomized, controlled trials powered detect difference complications determine whether reduces
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