Assisted human reproduction and pregnancy outcomes in Alberta, 2009–2018: a population-based study

• DOI: 10.9778/cmajo.20220073
• Publication Date: 2023-04-25T12:25:39Z
• Authors: Linn E. Moore; Morteza Haijhosseini; Tarek Motan; Padma Kaul
• Keywords: Human reproduction

Assisted human reproduction (AHR) can be used to help individuals and couples overcome infertility issues. We sought describe trends in pregnancies using AHR evaluate the impact of on perinatal outcomes a large population-based cohort Alberta, Canada.We linked maternal child administrative data for all live births occurring July 1, 2009, Dec. 31, 2018, Canada, this retrospective study. identified from pharmaceutical claims or codes International Classification Diseases Related Health Problems (9th 10th revision). Our main outcome measures were incidence temporal pregnancies. also compared characteristics non-AHR pregnancies, by age group.Of 518 293 during study period, 26 270 (5.1%) conceived with AHR. The increased 30.8 per 1000 2009 54.7 2018. Females who older (33.9 yr v. 30.1 yr, p < 0.001) number females aged 30-35 years than 35 delivered following over period (30-35 yr: 36.9 55.3 pregnancies; > 79.1 95.2 pregnancies). proportion cesarean delivery (40.5% 23.3%, 0.001), low birth weight (26.9% 7.6%, congenital malformation (0.5% 0.3%, = 0.002) admission neonatal intensive care unit (25.3% 9.7%, was higher group group.The Alberta 5.1% between 0.26% year; newborns appeared smaller showed signs poorer health. This provides insights potential complications that may important when caring newborn child.