Niraj Parajuli

ORCID: 0000-0001-6869-4959
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About
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Research Areas
  • Research on Leishmaniasis Studies
  • Dermatological diseases and infestations
  • Dermatology and Skin Diseases
  • Infectious Diseases and Tuberculosis
  • Urticaria and Related Conditions
  • Nail Diseases and Treatments
  • Autoimmune Bullous Skin Diseases
  • Parasitic Diseases Research and Treatment
  • Leprosy Research and Treatment
  • Dermatological and COVID-19 studies
  • Porphyrin Metabolism and Disorders
  • Skin and Cellular Biology Research
  • Skin Diseases and Diabetes
  • Parasites and Host Interactions
  • Autoimmune and Inflammatory Disorders
  • Eosinophilic Disorders and Syndromes
  • Cutaneous lymphoproliferative disorders research
  • Drug-Induced Adverse Reactions
  • Syphilis Diagnosis and Treatment
  • Dermatological and Skeletal Disorders
  • Contact Dermatitis and Allergies
  • Cutaneous Melanoma Detection and Management
  • Folate and B Vitamins Research
  • Atherosclerosis and Cardiovascular Diseases
  • melanin and skin pigmentation

Bir Hospital
2018-2025

National Academy of Medical Sciences
2018-2025

Earlham College
2018

Chitwan Medical College
2015-2017

Abstract World Neglected Tropical Diseases (NTD) Day on January 30th, with the theme ‘Unite. Act. Eliminate.’, emphasizes global fight against NTDs, underlining efforts to address inequalities that perpetuate NTDs. This article explores milestones and calls for sustained collaboration achieve a healthier, more equitable future vulnerable populations.

10.1093/jtm/taaf007 article EN Journal of Travel Medicine 2025-02-02

Abstract Cutaneous leishmaniasis cases have increased dramatically in recent years Nepal. The study offers molecular identification of the Leishmania species using 40 patient’s aspiration biopsy samples, targeting markers kinetoplast minicircle DNA (kDNA) and internal transcribed spacer-1 (ITS1). Among molecularly diagnosed 22 cutaneous cases, L. donovani complex was identified 13 instances major 9 cases. ITS1 PCR positive 12 nested- kDNA (12/22), confirming seven five In addition, conclude...

10.1038/s41598-023-37458-6 article EN cc-by Scientific Reports 2023-07-29

Chronic urticaria (CU) is a skin condition characterized by sudden and recurrent episodes of wheals, angioedema, or both commonly associated with itching for duration more than six weeks. The available data indicate that markedly affects objective functioning subjective well-being patients. A review patients’ records chronic attending Civil Service Hospital from January 2018 to December 2019 was done. detailed demographic all patients also retrieved. Dermatology Life Quality Index...

10.1155/2020/6694191 article EN cc-by Dermatology Research and Practice 2020-11-28

Background In Nepal, the burden of post kala-azar dermal leishmaniasis (PKDL) is not known since there no active case detection PKDL by national programme. patients could pose a challenge to sustain visceral (VL) elimination. The objective this study was determine prevalence and assess patients’ knowledge on VL PKDL, stigma associated with PKDL. Methodology/Principal findings Household surveys were conducted in 98 endemic villages five districts that reported highest number cases within...

10.1371/journal.pntd.0011138 article EN cc-by PLoS neglected tropical diseases 2023-02-09

Here we report on the pattern of dermatoses presented during a dermatological camp in Bharatpur prison. A total 119(27.2%) inmates out 437 had problem. Most common were skin infections (34.8%). Among infections, fungal most (82%). In non-infectious group eczematous disorders and pigmentary common. Overcrowding prison with three times excess could be contributing factor for infectionsDOI: http://dx.doi.org/10.3126/jcmc.v4i4.11968

10.3126/jcmc.v4i4.11968 article EN cc-by-nc Journal of Chitwan Medical College 2015-01-28

Anetoderma presents as a circumscribed area of slack skin. It can present either primary or secondary, if associated with other conditions. Leprosy is one the causes secondary anetoderma, but it not commonly reported, especially in multibacillary leprosy. Here, we report case 16-year-old young girl who presented fever, joint pain, and only three anetodermic plaques. A slit skin smear from lesion showed multiple acid-fast bacilli bacillary index 3+, thus confirming diagnosis This unique since...

10.1155/2020/8847310 article EN cc-by Case Reports in Dermatological Medicine 2020-07-29

Cutaneous tuberculosis is an uncommon form of extrapulmonary tuberculosis. It can present in various morphological presentations leading to a late diagnosis many cases. mainly associated with significant scarring and morbidity. classified as paucibacillary or multibacillary depending on the bacillary load. Similarly, it be acquired through either endogenous exogenous source. The mainstay treatment anti-tubercular medications. objective study was find out prevalence cutaneous among patients...

10.31729/jnma.7930 article EN Journal of Nepal Medical Association 2023-01-01

Cutaneous leishmaniasis (CL) can present with various skin lesions ranging from a single ulcer to diffuse multiple nodules. Here, we case of 67-year-old man large erythematous well-defined indurated plaque over the left face for duration 4 months. A slit smear was performed, and it stained Giemsa stain which showed amastigotes confirming diagnosis CL. Oral miltefosine started at dose 150 mg/day but had be stopped after 20 days as patient developed diarrhea, bipedal edema, renal impairment....

10.4269/ajtmh.20-0918 article EN American Journal of Tropical Medicine and Hygiene 2020-11-24

Background: Steroid-modified tinea, also known as tinea incognito, is an infection by the dermatophytes, where clinical morphology modified due to corticosteroids, either systemic or topical. Rampant use of topical corticosteroids has led increasing recurrence in infections. Methods: All consenting cases presenting outpatient department dermatology Civil Service Hospital from March August 2020 for a total 6 months were included this study. Tinea involving only palms, soles, nails scalp...

10.33314/jnhrc.v19i1.3105 article EN Journal of Nepal Health Research Council 2021-04-23

Background Chronic Spontaneous Urticaria is considered to be an autoimmune phenomenon in half of the total cases. Autologous serum skin test a simple screening for presence auto-antibodies chronic urticaria. Significant impairment quality life have been observed autologous positive There are limited literatures on spontaneous urticaria, and associated Dermatology Life Quality Index Nepal till date. Objective To find proportion cases urticaria such patients. Method This was retrospective...

10.3126/kumj.v20i4.54083 article EN Kathmandu University Medical Journal 2022-12-31

Introduction: Sexually transmitted infections (STIs) have a profound impact on sexual and reproductive health worldwide especially in developing country like Nepal. However, adequate studies are lacking our context with regards to the pattern analysis of STIs community tertiary care hospitals. The aim this study is understand prevalence different Nepal.
 Methods: This retrospective observational which record all patients who attended STD OPD NAMS, Bir Hospital from 2071 2075 B.S. (April...

10.3126/gmj.v1i2.27058 article EN Grande Medical Journal 2019-12-31

Dermatomyositis is an idiopathic muscle disease characterized by proximal weakness, raised enzymes, characteristic changes in electromyography and typical skin rash biopsy findings. Dermatological features like Gottron’s sign papules are considered as pathognomonic for dermatomyositis. Panniculitis one of the rare findings DM. Here, we report a case DM 37 years old female who presented with only panniculitis diagnosis was delayed more than year.

10.31729/jnma.4827 article EN cc-by Journal of Nepal Medical Association 2020-03-30

The diagnosis of cutaneous leishmaniasis is mostly confirmed by the identification parasitein a skin smear or biopsy. However, this method may not always be sensitive enough to detectthe disease when parasitic load low. Molecular test such as polymerase chain reactions canbe useful in circumstances. Here, we report case diagnosedby reaction both and biopsy failed confirm diagnosis.A 17-years-old female from mountainous district Nepal, presented with crusted plaqueover upper lip for duration...

10.31729/jnma.5025 article EN cc-by Journal of Nepal Medical Association 2020-07-31

Nepal attained the status of leprosy elimination as a public health problem in 2010, however still struggling to sustain it.A recent World Health Organization (WHO) report has shown an increase new case detection from 2019 (3,844 cases) which is alarming situation [1].In effort and reduce transmission, postexposure prophylaxis (LPEP) with single-dose rifampicin (SDR) been implemented some districts part national control program.The differences opinions among experts on LPEP created certain...

10.1371/journal.pntd.0009039 article EN cc-by PLoS neglected tropical diseases 2021-04-08

Background: Acne causes significant impairment in the quality of life patients, but clinicians Nepal lack a simple validated tool to measure psychological side acne. We planned translate and validate Cardiff Disability Index, five item questionnaire into Nepali language address this need.Methods: A linguistic translation with semantic equivalence original English Index was achieved through standard forward backward language. All eligible patients were requested fill translated version both...

10.33314/jnhrc.v20i3.4070 article EN Journal of Nepal Health Research Council 2023-03-09

Genodermatoses are group of genetic disorders that present with cutaneous manifestations. The exact prevalence on many these conditions unknown due to its rarity, need specialized tests for diagnosis and lack proper reporting system. Most the patients faced life-long disability associated stigma. There is a centers very elaborated yet simple system in Nepal. These rare should be kept priority by government align sustainable development goals ensure healthy-lives promote well-being all. A...

10.33314/jnhrc.v20i4.4520 article EN PubMed 2023-07-20

Abstract Skin neglected tropical diseases (NTDs) are a group of that present with cutaneous manifestation. There at least 12 listed included in the list skin NTDs by World Health Organization. Among these, some typically more commonly certain geographical locations compared others. For example, leprosy is common Asian subcontinent and Buruli ulcer African region. In this new world easy global reach due to ease travel, not restricted only tropics. Despite propensity these occur tropics among...

10.1093/bjd/ljae090.346 article EN other-oa British Journal of Dermatology 2024-06-28

Cutaneous larva migrans is a tropical dermatosis acquired through the helminthic infection. It caused by penetration of animal hookworm in patient with history walking barefoot on soil or beaches travel to areas. usually presents clinically as pruritic serpiginous lesion trailing. Here, we report three cases who presented asymptomatic thread like cutaneous examination. was diagnosed and proper treatment done complete regression manifestations within week. Although condition self-limiting, it...

10.33314/jnhrc.v22i03.5210 article EN Journal of Nepal Health Research Council 2024-12-20

The skin diseases of pediatric population are varied which change according to age and season. There is a rarity studies on conditions from Nepal. This observational study the only tertiary care referral center country highlighted burden in Nepalese population. All new cases patients less than 14 years consulting dermatological OPD Kanti Children’s Hospital January 2017 December were included this study. Demographic details all such as sex recorded. diagnosis was made clinically most...

10.1155/2021/6619936 article EN cc-by Dermatology Research and Practice 2021-06-12

Introduction: Sexually transmitted infections (STIs) are the diseases that by sexual contact if a partner is infected with agent known to cause infection of genitalia. This group pose huge public health problem. study aims provide an insight on prevalence STIs in tertiary care center dedicated civil servants. Methods: retrospective cross-sectional study. All patients diagnosed STI dermatology out-patient Civil Service Hospital, hospital situated Kathmandu over period two years from January 1...

10.3126/njdvl.v19i2.37686 article EN cc-by Nepal Journal of Dermatology Venereology & Leprology 2021-10-04

Introduction: Acne vulgaris is a self-limited disorder of the pilosebaceous unit. It primarily seen in adolescent age group. can present with pleomorphic lesions consisting comedones, papules, pustules and nodules. Both inflammatory non-inflammatory acne produce scarring. has been found that significantly affects self-image quality life. Effective treatment results improvement life.Objective: The objective this study was to find impairment life patients acne.Materials Methods: A total 140...

10.3126/njdvl.v16i1.19406 article EN Nepal Journal of Dermatology Venereology & Leprology 2018-03-29

Introduction: Patch testing is a diagnostic tool used in investigation to identify specific allergens allergic contact dermatitis (ACD). It helps find the prevalence and trends of sensitization community.
 Objective: To report two year patch test results from central hospital Kathmandu.
 Materials Methods: Consecutive consenting patients suspected ACD were tested with an Indian standard Series (Systopic) June 2014 August 2016.
 Results: Out 141 tested, 89 female (63.12%) 52...

10.3126/njdvl.v17i1.23118 article EN Nepal Journal of Dermatology Venereology & Leprology 2019-03-31
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