A5084045326- Synthesis and Catalytic Reactions
- Catalytic C–H Functionalization Methods
- X-ray Diffraction in Crystallography
- Chemical Synthesis and Reactions
- Crystallization and Solubility Studies
- Sulfur-Based Synthesis Techniques
- Chemical Synthesis and Analysis
- Asymmetric Hydrogenation and Catalysis
- Multicomponent Synthesis of Heterocycles
- Asymmetric Synthesis and Catalysis
- Synthetic Organic Chemistry Methods
- Crystallography and molecular interactions
- Carbon dioxide utilization in catalysis
- Synthesis of Indole Derivatives
- Synthesis of β-Lactam Compounds
- Inorganic and Organometallic Chemistry
Visva-Bharati University
2015-2020
University of Calcutta
2019
An imidazole-based zwitterionic-salt, 4-(3-methylimidazolium)butane sulfonate (MBS), has been used as organocatalyst for regioselective ring-opening of aziridine by various nucleophiles.
Aziridines are highly versatile intermediates in organic synthesis due to their easy access and susceptibility ring-opening by facile C-N bond cleavage. They synthetically very important as they valuable precursors of amino sugars, β-lactam antibiotics alkaloids or present various natural products that exhibit potent biological activities. The this moiety from the easily available chemicals is desirable its tremendous use branches chemistry. Here, a short review has been reported on scaffold...
This account discusses the use of aqueous zinc(II) tetrafluoroborate as a mild and selective catalyst for various important organic transformations. In general, advantages methodologies discussed include high yields; short reaction times; excellent regio-, chemo-, stereoselectivities; conditions; efficiency. The in synthesis antihypertensive drug metoprolol is also discussed. 1 Introduction 2 Protection Deprotection 2.1 Selective <i>tert</i>-Butyl(dimethyl)silyl Ethers...
Abstract We have developed a convenient method to synthesize tertiary amines selectively with variety of aldehydes and primary using commercially available formic acid as reducing agent. In our methodology we shown that can prepare by changing both the well aldehydes. Clean reaction, operational simplicity, easily accessible reactants, metal solvent‐free environmentally friendly reaction conditions are notable advantages this procedure.
We have developed a new synthetic method for the synthesis of aziridines using Chloramine-T as an effective reagent in presence NH2OH·HCl and NaIO4. found that same combination NaIO4 is also very nucleophilic ring opening aziridines.
Abstract Synthesis of oxazolidines has been reported from aziridines by the reaction with formic acid and formaldehyde in neat conditions. We have also observed a regio‐selective nucleophilic ring opening HCOOH under same conditions absence where HCOO − ion acts as nucleophile. In this present method is not acting reducing agent classical organic reactions. The initially activates whereas formate group generated nucleophile itself instead source hydride affording products. synthesized ester...
An aprotic imidazole based zwitterionic-salt, 4-(3-methylimidazolium)-butane sulfonate has been found to be an efficient organocatalyst for tetrahydropyranylation by the reaction of 3,4-dihydro-2H-pyran (DHP) and different aliphatic alcohols as well various phenolic compounds. The notable advantages present method are general applicability alcohols, clean reaction, production no hazardous waste, open air conditions high yields. catalyst can reused without loss significant catalytic activity.
The synthesis of vicinal diiodo carbonyl compounds from α,β-unsaturated has been carried out for the first time using combination NH2OH•HCl and NaIO4 under mild reaction conditions at room temperature.The present methodology is also applicable derivatives nitrostyrene.The remarkable advantages protocol are temperature reaction, easy operation, good yields, fast transition metalfree neutral conditions.The to gram scale synthesis.
Abstract It has been observed that CuO nanoparticles act as effective and reusable catalyst for the ring‐opening reaction of aziridines with a wide range nucleophiles such alcohols, thiols, indoles. The catalytic activity tested in large scale reactions. methodology is applicable very low loading. proceeds under solvent‐free conditions. used six consecutive cycles comparable efficiency. present could be considered environmentally benign indicated by calculation E‐factors which are 0.37–1.31.
A very simple approach has been developed for conjugate addition of a variety aliphatic and aromatic amines to electron deficient alkenes in presence tea extract at room temperature. General applicability, operational simplicity, aqueous media, mild reaction conditions, environment friendly, high yields applications inexpensive easily available catalyst are the advantages present procedure.
Abstract Review: [27 refs.
Abstract The aziridine ring is regioselectively opened by various nucleophiles, such like indoles, methanol, acetic acid, and di‐isopropylamine.