A5043743019- Diabetes Treatment and Management
- Diabetes Management and Research
- Diabetes and associated disorders
- Metabolism, Diabetes, and Cancer
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diet and metabolism studies
- Pancreatic function and diabetes
- Peroxisome Proliferator-Activated Receptors
- Glaucoma and retinal disorders
- Diet, Metabolism, and Disease
- Case Reports on Hematomas
- Retinal Imaging and Analysis
- Pharmacology and Obesity Treatment
- Blood Pressure and Hypertension Studies
- Apelin-related biomedical research
- Gout, Hyperuricemia, Uric Acid
- Lipoproteins and Cardiovascular Health
- Neurological Disorders and Treatments
- Neurological Disease Mechanisms and Treatments
- Cancer, Lipids, and Metabolism
- Clinical practice guidelines implementation
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiovascular Health and Risk Factors
- Alcohol Consumption and Health Effects
- Retinal Diseases and Treatments
Zhongshan People's Hospital
2006-2020
The First Affiliated Hospital, Sun Yat-sen University
2020
Sun Yat-sen University
2020
Zhongshan Hospital
2020
Second Hospital of Hebei Medical University
2006
Hebei Medical University
2006
This study investigated the prevalence and determinants of hyperuricemia in Chinese type 2 diabetes mellitus (T2DM) patients with central obesity. A multicentric hospital-based cross-sectional was carried out Guangdong Province between August 2011 March 2012. At each hospital, T2DM obesity who were aged over 20 years, whose serum uric acid levels measured, had lived for >=1 year, recruited. Hyperuricemia defined as >420 μmol/L men >360 women. Binary logistic regression used to assess...
Chiglitazar (Carfloglitazar) is a novel peroxisome proliferator-activated receptor (PPAR) pan-agonist that has shown promising effects on glycemic control and lipid regulation in patients with type 2 diabetes. In this randomized phase 3 trial, we compared the efficacy safety of chiglitazar sitagliptin diabetes who had insufficient despite strict diet exercise regimen. Eligible were (1:1:1) to receive 32 mg (n = 245), 48 246), or 100 248) once daily for 24 weeks. The primary endpoint was...
Glycaemic control is a great challenge in the management of type 1 diabetes mellitus (T1DM). There limited data concerning glycaemic among adults with T1DM. We used from Guangdong T1DM Translational Medicine Study to evaluate and its associated factors Chinese T1DM.This cross-sectional analysis included 827 participants who were 18 years age or older had been living for at least year. Participants HbA1c levels <7% compared against those ≥ 7%. A multivariate logistic regression model was...
Abstract Background A lack of demographic and clinical data hinders efforts health care providers in China to support patients with type 1 diabetes mellitus (T1D). Therefore, the aim present retrospective study was provide an overview characteristics Chinese T1D. Methods Hospital medical records T1D (diagnosed between January 2000 December 2011) 105 secondary tertiary hospitals across Guangdong province were reviewed. Data collected on patient age at diagnosis, presentations onset, physical...
Background Type 2 diabetes is often accompanied by altered cardiometabolic risk profiles, including abdominal obesity, hypertension, and dyslipidaemia. The association of profiles with chronic complications not well investigated. Methods We recruited 2954 type patients a body mass index ≥25 kg/m2 who visited the clinics 62 hospitals in 21 cities Guangdong province China from August 2011 to March 2012. Demographic characteristics, personal family medical histories, data on were collected....
Introduction. Diabetic retinopathy (DR) is a common chronic microvascular diabetic complication. The presence of DR may indicate microcirculatory dysfunction in other organ systems besides visual morbidity. objective this study was to develop simple risk score identify Chinese overweight/obese patients with type 2 diabetes mellitus (T2DM).Patients and methods. A multicentre hospital-based cross-sectional carried out Guangdong Province between August 2011 March 2012. evaluated 2699 included...
Limited data on the efficacy of additional metformin therapy in patients with type 1 diabetes mellitus (T1DM) under real-life conditions have been available so far.Patients aged ≥18 years a duration T1DM for at least year were included this multicenter observational study. Patients insulin combined (MET group) compared those only (INS group).A total 76 MET group 655 INS group. At baseline, dyslipidemia more prevalent (17.6% vs 9.0%; P = .006), and they also had higher body mass index (BMI)...
Chiglitazar, a novel PPARα/γ/δ pan-agonist, showed favorable effects on glycemic control and lipid modulation with well tolerated safety profile in phase 2 trials. This trial aimed to compare the efficacy of chiglitazar DPP-4 inhibitor sitagliptin patients type diabetes inadequately controlled diet exercise (ClinicalTrials.gov NCT02173457). Patients were randomly assigned receive 32 mg or 48 mg, 100 once daily. The primary endpoint was change HbA1c from baseline at week 24, non-inferiority...
Objective To evaluate the efficacy and safety of glargine insulin injection (Uslen) in treatment diabetic patients. Methods A multicenter, randomized, open-labeled positive control clinical trial included patients with type 1 or 2 diabetes mellitus having poor glucose after using oral antidiabetic drug short-acting insulin. All were treated Uslen Lantus for 16 weeks two groups by a ratio 1∶1. The decreased value qualification rates glycated hemoglobin A1c(HbA1c) fasting blood (FBG),...
Objective To evaluate the effects of diet and exercise lifestyle intervention to glucose metabolism overweight obese type 2 diabetic patients.Methods This survey randomly recruited 244 patients.According Chinese Guideline on Prevention Treatment Type Diabetes,a cross-sectional investigation was performed targeted status blood sugar glycated hemoglobin (HbAlc).This investigated patients whether they had or not; also compared between group without intervention.Results By comparing with fasting...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Objective To explore the effect of walking on residual beta cell function and glycemic control in patients with type 1 diabetes mellitus. Methods A total 117 mellitus who usually walked less than 5000 steps per day were given health education about exercise divided into three groups according to their self-estimates number they had taken daily previous 4 months: an absent group ( 10000 steps/day). Among them, 34 (23.5% for males), 45 basis (40.0% males) 38 active (52.6% males)....