A5001334042- Neonatal Respiratory Health Research
- Metabolism and Genetic Disorders
- Nitric Oxide and Endothelin Effects
- Urological Disorders and Treatments
- Neuroscience of respiration and sleep
- interferon and immune responses
- Pediatric Hepatobiliary Diseases and Treatments
- Birth, Development, and Health
- Neonatal Health and Biochemistry
- Congenital Heart Disease Studies
- Attention Deficit Hyperactivity Disorder
- Pediatric Urology and Nephrology Studies
- Fetal and Pediatric Neurological Disorders
- Pulmonary Hypertension Research and Treatments
- Cardiovascular Conditions and Treatments
- Cerebral Venous Sinus Thrombosis
- Congenital Anomalies and Fetal Surgery
- Infant Development and Preterm Care
- Hepatitis Viruses Studies and Epidemiology
- Ion Transport and Channel Regulation
- Neurotransmitter Receptor Influence on Behavior
- Neurogenetic and Muscular Disorders Research
- Neuropeptides and Animal Physiology
- Autism Spectrum Disorder Research
- Blood groups and transfusion
Gaziantep University
2006-2016
Hacettepe University
2004-2010
Hacettepe University Hospital
2005
Transcatheter closure of a patent ductus arteriosus (PDA) has always been considered risky for infants weighing <6 kg and preterms. We present our findings regarding transcatheter closures PDA.The inclusion criteria were weight the presence PDA symptoms. The study subjects divided into two groups: premature infants.A total 69 included. mean ages weights preterms 5.4 ± 2.7 months 30.3 19.9 days, 4.6 0.8 1.7 0.3 kg, respectively. Type C PDAs most frequently observed in group, type A was kg....
The purpose of this study was to evaluate the relationship between attention deficit hyperactivity disorder (ADHD) and polymorphism two regions 5-HTT gene [variable number tandem repeats (VNTR) 5-HTTLRR] in a sample Turkish children. Using PCR technique, these polymorphisms were assessed 71 patients with ADHD 128 healthy controls. 5-HTTLPR S/S genotype significantly lower than controls (p = 0.018). Homozygous heterozygous L variant predominated group. But VNTR STin2.12/12 less found 0.001)....
Several studies indicate that nitric oxide (NO) is involved in the aetiopathogenesis of many neuropsychiatric disorders such as schizophrenia, bipolar disorder, depression, Alzheimer's disease, Hungtington disease and stroke. Although it has not been investigated yet, several recent proposed NO may have a pathophysiological role autism. Adrenomedullin (AM), recently discovered 52-amino acid peptide hormone, induces vasorelaxation by activating adenylate cyclase also stimulating release. AM...
Disturbances in the serotonergic neurotransmission system have been implicated etiology of attenion deficit/hyperactivity disorder (ADHD). As importance genetic factors is well established, genes encoding for proteins pathway are important candidates to unravel underlying contribution. We previously demonstrated that polymorphisms serotonin transporter gene promoter and regions variable number tandem repeats were involved pathogenesis ADHD. The purpose this study was examine relationship...
The aim of this study was to determine mortality risk by calculating Score for Neonatal Acute Physiology and Perinatal Extension II (SNAP-PE-II) Clinical Risk Index Babies (CRIB) score, evaluate prediction the effects antenatal corticosteroid surfactant treatment on mortality.This multicenter conducted simultaneously in five different centers four provinces Southern Turkey between July 2012 2013. A total 1668 inborn subjects hospitalized neonatal intensive care unit within first 12 h...
Respiratory distress syndrome (RDS) of the newborn is one most common causes morbidity and mortality in preterm infants. Our objective was to determine association between Rho-kinase (ROCK1 ROCK2) gene polymorphisms RDS neonates.A total 193 infants with 186 without respiratory problems were included this study. Polymorphisms analyzed genomic DNA using a BioMark 96.96 dynamic array system.We observed that ROCK1 rs2271255 (Lys222Glu) rs35996865 polymorphisms, ROCK2 rs726843, rs2290156,...
Thalassemia is one of the most common hereditary disorders in Mediterranean region and studies have shown that prevalence beta-thalassemia trait high southern part Turkey. Gaziantep a city located near this and, therefore, authors investigated hematological characteristics traits primary school students Gaziantep. Sixty schools were selected from list all using systematic sampling method. Data collected by face-to-face questionnaire. Osmotic fragility testing (OFT) single-tube 0.36% NaCl...
Abstract Rationale Respiratory Distress Syndrome (RDS) due to prematurity is one of the most important causes morbidity and mortality in Neonatal Intensive Care Units. According few studies recent years, endothelial nitric oxide synthase (eNOS) gene polymorphisms are found be partially responsible for liability RDS. The purpose this study was determine association between eNOS polymorphism RDS preterm neonates. Patients Methods patient group consisted 152 premature neonates born before 37...
Uhl's anomaly was first reported by Uhl in 1952 and is characterized congenital partial or complete absence of right ventricular myocardium. It a very rare with unknown aetiology. Associations other heart diseases, familial occurrency, sudden death arrhythmia have been reported. Pathologic findings vary the patient's age severity disorder. In infancy, it may occur severe right-sided failure as well asymptomatic cardiomegaly. Despite its rarity, be considered patients due to dilated...
Gallbladder (GB) perforation is a rare complication of acute acalculous cholecystitis. This mostly manifests as free into the peritoneal cavity, subacute pericholecystic abscess, or chronic with cholecystoenteric fistula. Perforation GB liver extremely rare, and was reported only in adults, whom all were treated surgically. The authors present an intrahepatic secondary to cholecystitis, its successful conservative management 13-year-old boy.
Meningitis is an inflammatory disease caused by bacteria, fungi, and viruses with various clinical symptoms. Interleukin-10 (IL-10) levels have been shown to be increased in blood or cerebrospinal fluid of patients meningitis, but the association IL-10 gene promoter polymorphisms expression meningitis has not evaluated. A-592C, T-819C, A-1082G 61 64 healthy controls were determined real-time polymerase chain reaction analysis. mRNA from samples was extracted, performed for expression. No...
Meningitis is an inflammation of the protective membranes covering brain and spinal cord caused by bacteria, fungi, or viruses with various clinical symptoms. Although meningitis not so prevalent, it remains most serious contagious disease. The aim our study was to investigate effect gene expressions nitric oxide synthases (NOS) on patients. Using samples taken from 61 patients, inducible NOS, endothelial NOS (eNOS), neuronal mRNA levels were assessed in both blood cerebrospinal fluid (CSF)....