- Neural Interface Technology
- Pathophysiology of Lumbar Disc Degeneration and Treatment
- Neuro-Immune Modulation via Vagus Nerve Stimulation
- Impact of Spinal Deformity on Health and Function
- Analysis of Electromyography Signal Processing
- Management and Treatment of Peripheral Arterial Disease
- Design and Management of Water Distribution Networks
- Spinal Hematomas and Related Conditions
- Cholesterol-lowering Treatment
- Spontaneous Pneumomediastinum in COVID-19 Patients
- Advanced Cardiac Imaging Techniques and Diagnostics
- Prevention and Management of Postoperative Nausea and Vomiting
- Diagnosis and Management of Endometriosis
- Roles of Neurotrophins in Nervous System Function
- Management of Mesenteric Ischemia and Aneurysms
- Catheter Ablation of Cardiac Arrhythmias
- Management of Postoperative Pain and Complications
- Seismic Design and Analysis of Underground Structures
- Pregnancy-related Pelvic Girdle and Low Back Pain
- Challenges in Pain Management and Treatment
- Conducting Polymer Research
- Perioperative Cardiac Risk Assessment and Management
- Cardiac Resynchronization Therapy in Heart Failure
- Modeling and Assessment of Pipeline Corrosion Damage
- Spine Surgery Techniques and Technologies
University Hospital of Bern
2005-2024
University of Bern
2006-2024
University of Indianapolis
2021-2023
Indiana University – Purdue University Indianapolis
2021-2023
Rush University Medical Center
2019-2020
Purdue University West Lafayette
2019
Kantonsschule Olten
2006
Swiss Continence Foundation
2005
In Switzerland, approximately 32,000 patients are hospitalized annually due to adverse drug reactions (ADRs), representing 2.3% of all hospitalizations. During the perioperative period, administration a variety drugs from different classes over relatively short period time increases risk ADR. Here, we describe case 32-year-old woman who was administered droperidol treat nausea in recovery room after myomectomy and subsequently became comatose. Correctable metabolic, respiratory,...
The intrinsic electrical material properties of the laminar components mammalian peripheral nerve bundle are important parameters necessary for accurate simulation interaction between fibers and neural interfaces. Improvements in accuracy these improve realism enables realistic screening novel devices used extracellular recording stimulation nerves. This work aims to characterize nerves build upon resistive parameter set established by Weerasuriya et al. 1984 amphibian somatic (frog sciatic...
Health-related quality of life in adults with congenital cardiac disease appears to be impaired, but the determinants this alteration remain largely unknown. The aim our study was examine impact arrhythmias on patients late after atrial redirection operation for transposition, or complete correction tetralogy Fallot.We enrolled 32 and 35 Fallot, a prospective study. Quality assessed using RAND-36 questionnaires. data were compared those an age-matched control population. Patients underwent...
Retrospective cohort.To determine how the number of fused intervertebral levels affects radiographic parameters and clinical outcomes in patients undergoing open posterolateral lumbar fusion (PLF) for low-grade degenerative spondylolisthesis.This was a retrospective cohort study on who underwent PLF spondylolisthesis at single institution from 2011 to 2018. Patients were divided into groups based during their procedure (1, 2, or 3 more). Preoperative postoperative spinopelvic parameters,...
This paper describes a method to reversibly block nerve conduction through direct application of 1 Hz sinusoidal current waveform delivered bipolar cuff electrode. low frequency alternating (LFAC) was previously shown the effects vagal pulse stimulation evoked bradycardia in-vivo in anaesthetised rat model (Mintch et al. 2019). The present work measured effectiveness LFAC on larger caliber myelinated afferent fibers human sized bundles projecting changes breathing rate mediated by...
(1) Background: The aim of this study was to evaluate the impact endometriosis on postoperative pain following laparoscopic hysterectomy; (2) Methods: A total 214 women who underwent a hysterectomy between January 2013 and October 2017 were divided into four subgroups as follows: with chronic before surgery (n = 57); pain-free 50); (3) without 40); (4) absence both preoperative 67). Postoperative compared by using Visual Analog Scale (VAS) scores tracking use painkillers during day first two...
Background Improved endothelial function may contribute to the beneficial effects of cholesterol lowering therapy in patients with coronary artery disease (CAD), but results effect statin on are disparate these patients. Exercise training has been reported improve at risk or established CAD. The goal study was compare mild exercise forearm CAD average levels. Design and methods Twenty-eight sedentary male angiographically documented pretreatment total plasma levels (5.1±0.9 mmol/l) aged...
The sinusoidal low-frequency alternating current (LFAC) waveform was explored recently as a novel means to evoke nerve conduction block. In the present work, we whether increasing amplitude of LFAC results in fiber activation autonomic nerves. In-silico methods and preliminary work somatic nerves indicated potential frequency dependency on threshold activation. Hering-Breuer (HB) reflex used biomarker detect cervical vagus activation.Experiments were conducted isoflurane-anesthetized swine...
The stimulation and recording performance of implanted neural interfaces are functions the physical electrical characteristics interface, its electrode material structure. Therefore, rapid optimization such is becoming critical in most clinical research studies. This paper describes development an upgraded 3D printed cuff shell design containing a novel intrinsically conductive polymer (ICP) for peripheral nerve fibers.A stereolithography (SLA) printer was used to print scalable, custom...
Les facteurs cardiaques sont responsables de 40% la morbidité et mortalité des interventions chirurgicales non cardiaques. L’évaluation préopératoire du risque cardiovasculaire joue donc un rôle essentiel.
Purpose: Pneumoperitoneum with diffuse abdominal pain and elevated inflammatory serum markers generally results from free perforation of an hollow organ requiring emergency surgical exploration. In contrast, we present the case a patient intraperitoneal air as manifestation pneumatosis coli which could be treated conservatively. Results: Case: A 50 year old female history chronic obstructive pulmonary disease recurrent embolism oral anticoagulation presented to department melena pain. On...