A5058600075- Nanoparticle-Based Drug Delivery
- Graphene and Nanomaterials Applications
- Industrial Vision Systems and Defect Detection
- Nanocluster Synthesis and Applications
- Optical measurement and interference techniques
- Advanced Memory and Neural Computing
- Gold and Silver Nanoparticles Synthesis and Applications
- Advanced Drug Delivery Systems
- Advanced Optical Imaging Technologies
- Neural Networks and Applications
- Infrastructure Maintenance and Monitoring
- Manufacturing Process and Optimization
- Orbital Angular Momentum in Optics
- RNA Interference and Gene Delivery
- Structural Health Monitoring Techniques
- Supramolecular Self-Assembly in Materials
- High Entropy Alloys Studies
- Machine Learning and ELM
- Chemical Thermodynamics and Molecular Structure
- Wireless Signal Modulation Classification
- Vehicle License Plate Recognition
- Quantum Mechanics and Applications
- Advanced Image Fusion Techniques
- Synthesis and Properties of Aromatic Compounds
- Advanced Fluorescence Microscopy Techniques
University of Electronic Science and Technology of China
2023-2024
Second Hospital of Shandong University
2024
Shanghai Jiao Tong University
2024
Changchun Institute of Optics, Fine Mechanics and Physics
2020-2023
Chinese Academy of Sciences
2020-2023
University of Chinese Academy of Sciences
2022-2023
Otto-von-Guericke University Magdeburg
2018-2021
University Hospital Leipzig
2021
Kettering University
2020
Xiangtan University
2020
Development of functional materials capable exhibiting chirality tunable circularly polarized luminescence (CPL) is currently in high demand for potential technological applications. Herein we demonstrate the formation both left- and right-handed fluorescent helical superstructures from each enantiomer a chiral tetraphenylethylene derivative through judicious choice solution processing conditions. Interestingly, aggregation induced emission active enantiomers exhibit handedness inversion...
A delivery platform with highly selective permeability through the blood-brain barrier (BBB) is essential for brain disease treatment. In this research, we designed and prepared a novel target nanoplatform, that is, layered double hydroxide (LDH) nanoparticle conjugated targeting peptide-ligand Angiopep-2 (Ang2) or rabies virus glycoprotein (RVG) via intermatrix bovine serum albumin targeting. vitro studies show functionalization ligand significantly increases efficiency of LDH nanoparticles...
Fluorescently labeled nanoparticles are widely used for evaluating their distribution in the biological environment. However, dye leakage can lead to misinterpretations of nanoparticles’ biodistribution. To better understand interactions dyes and environment, we explored PLGA with four encapsulated (coumarin 6, rhodamine 123, DiI) or bound covalently polymer (Cy5.5.). The DiI label was stable both aqueous lipophilic environments, whereas quick release coumarin 6 observed model media...
Density (ρ) and viscosity (η) were determined over the whole concentration range for binary mixtures of 1,2-diaminoethane + 1,2-ethanediol at (298.15, 303.15, 308.15) K. The experimental results are compared with data published in previous literature. density values used to calculate excess molar volume (VmE). calculated fitted a Redlich−Kister equation obtain coefficients estimate standard deviations between quantities. VmE negative entire composition range.
Superparamagnetic iron oxide nanoparticles (SPIO-NPs) have great potential to be used in different pharmaceutical applications, due their unique and versatile physical chemical properties. The aim of this study was quantify vitro cytotoxicity dextran 70,000-coated SPIO-NPs labelled/unlabelled with rhodamine 123, C6 glioma cells primary hippocampal neural cells. In addition, we analyzed the vivo cellular uptake labelled SPIO-NPs. nanoparticles, average size 10–50 nm polydispersity index 0.37,...
Eyebox uniformity is an important indicator to evaluate the performance of optical waveguide displays. However, there currently no standard design approach that achieves ideal over full field view (FOV) within eyebox. Here, a novel method for eyebox optimization based on linked list processing proposed. The can fast record light trajectory and calculate optimal numerical diffraction efficiency distribution coupler. We use L-shaped diffractive solve matched coupler structure by combining...
The combination of Spiking Neural Networks (SNNs) and Vision Transformers (ViTs) holds potential for achieving both energy efficiency high performance, particularly suitable edge vision applications. However, a significant performance gap still exists between SNN-based ViTs their ANN counterparts. Here, we first analyze why suffer from limited identify mismatch the vanilla self-attention mechanism spatio-temporal spike trains. This results in degraded spatial relevance temporal interactions....
Much effort has been devoted to the discovery of effective biomaterials for nerve regeneration. Here, we reported a novel application gold nanoparticles (AuNPs) modified with 6-mercaptopurine (6MP) and neuron-penetrating peptide (RDP) as neurophic agent promote proliferation neurite growth human neuroblastoma (SH-SY5Y) cells. When cells were treated 6MP-AuNPs-RDP conjugates, they showed higher metabolic activity than control. Moreover, SH-SY5Y transplanted onto surface coated examine effect...
Hearing deficits impact on the communication with external world and severely compromise perception of surrounding. Deafness can be caused by particular mutations in neuroplastin (Nptn) gene, which encodes a transmembrane recognition molecule immunoglobulin (Ig) superfamily plasma membrane Calcium ATPase (PMCA) accessory subunit. This study investigates whether complete absence or loss adult after normal development lead to hearing impairment mice analyzed behavioral, electrophysiological,...
Abstract: Despite the significant progress in molecular imaging technologies that has been made recent years, specific detection of neural cells still remains challenging. Here, we suggest use gold nanoclusters (AuNCs) modified with a brain-targeting peptide as potential candidate for detecting vitro and mice. AuNCs less than 10 nm (dynamic light scattering analysis) were first prepared using “green” synthetic approach, then targeting peptide, rabies virus glycoprotein derived (RDP), was...
Objective: There is 25–35% mutation rate of p53 in cancerous neural cells and this reaches 70–76% glioma cell line. Complement wild-type has become a potential strategy for protein therapy cells. Here we investigated the feasibility novel RDP-p53 fusion anti-proliferation possible mechanism, which would provide an effective approach targeted delivery to treat cells.Methods: The proteins are expressed Escherichia coli, they labeled with FITC rhodamine B by chemical modification....
Abstract: Highly-efficient delivery of macromolecules into cells for both imaging and therapy (theranostics) remains a challenge the design system. Here, we suggested novel hybrid protein–lipid polymer nanocapsule as an effective nontoxic drug carrier. The biodegradable nanocapsules showed typical double emulsion features, including fluorescently labeled bovine serum albumin shell, oil phase containing poly(lactic-co-glycolic acid) linoleic acid, inner aqueous phase. were spherical in shape,...
We demonstrate a 2.08 µm all-polarization-maintaining (PM) holmium-doped fiber oscillator using hybrid mode-locking technique with nonlinear polarization evolution (NPE) and semiconductor saturable absorber mirror (SESAM). This features linear structure dual output ports. It initiates stable single-pulse at fundamental repetition rate of 57.86 MHz, requiring only about 400 mW pump power. However, removing SESAM requires increasing the power to 2.2 W—about 5.8-fold increase—to initiate...
Recent works have demonstrated the effectiveness of retrieval augmentation in Event Argument Extraction (EAE) task. However, existing retrieval-based EAE methods two main limitations: (1) input length constraints and (2) gap between retriever inference model. These issues limit diversity quality retrieved information. In this paper, we propose a Compressive Memory-based Retrieval (CMR) mechanism for EAE, which addresses limitations mentioned above. Our compressive memory, designed as dynamic...
Images captured in low-brightness environments typically have low brightness, contrast, and high noise levels, which significantly affect the overall image quality. To improve quality, a enhancement algorithm based on multi-scale fusion is proposed. First, novel brightness transformation function used for generation of two images with different brightnesses. Then, illumination estimation technique to construct weight matrix, facilitates extraction advantageous features from each image....
In this Letter, we present a display system based on curved screen and parallax barrier, which provides stereo images with horizontal field of view 360° without wearing any eyewear, to achieve an immersive autostereoscopic effect. The principle characteristics are studied theoretically in detail. Three consecutive pixels barrier form unit, can generate separate viewing zones for the left right eyes, respectively. Simulation experimental results show that non-crosstalk effect be obtained...