A5013924873- Bone health and osteoporosis research
- Bone health and treatments
- SARS-CoV-2 and COVID-19 Research
- Geography and Environmental Studies
- Vitamin D Research Studies
- Agricultural and Food Sciences
- Thyroid Disorders and Treatments
- COVID-19 Clinical Research Studies
- Bone Metabolism and Diseases
- Thyroid Cancer Diagnosis and Treatment
- Diet and metabolism studies
- Soil and Land Suitability Analysis
- Medical and Biological Ozone Research
- Adipose Tissue and Metabolism
- Ion channel regulation and function
- Alkaline Phosphatase Research Studies
- Medical Imaging Techniques and Applications
- Respiratory viral infections research
- Hormonal and reproductive studies
- Viral gastroenteritis research and epidemiology
- Listeria monocytogenes in Food Safety
- Neuroendocrine Tumor Research Advances
- Hormonal Regulation and Hypertension
- Public Health in Brazil
- Biochemical Analysis and Sensing Techniques
Universidade do Porto
2023-2024
University of Trás-os-Montes and Alto Douro
2024
Universidade de São Paulo
2008-2024
Hospital de Santa Maria
2010-2023
Instituto Butantan
2023
University of Lisbon
2010-2023
Hospital da Senhora da Oliveira Guimarães
2023
Federal Institute of São Paulo
2021
Universidade Estadual Paulista (Unesp)
2009-2019
Universidade Federal de Alagoas
2018
The SARS-CoV-2 pandemic have been affecting millions of people worldwide, since the beginning 2020. COVID-19 can cause a wide range clinical symptoms, which varies from asymptomatic presentation to severe respiratory insufficiency, exacerbation immune response, disseminated microthrombosis and multiple organ failure, may lead dead. Due rapid spread SARS-CoV-2, development vaccines minimize severity in world population is imperious. One employed techniques produce against emerging viruses...
The ongoing COVID-19 pandemic represents an extra burden in the majority of public and private health systems worldwide beyond most pessimistic expectations, driving urgent rush to develop effective vaccines medical treatments against SARS-CoV-2 pandemic. Nucleocapsid structural viral protein is remarkably immunogenic hugely expressed during infection. High IgG antibodies (N protein) levels were detected serum patients, confirming its pivotal antigen role for a T lymphocyte response vaccine...
Although the exact mechanism of pathogenesis coronavirus SARS-CoV-2 (COVID-19) is not fully understood, oxidative stress and release pro-inflammatory cytokines have been highlighted as playing a vital role in disease. In this sense, alternative treatments are needed to reduce level inflammation caused by COVID-19. Therefore, study aimed investigate potential effect red photobiomodulation (PBM) an attractive therapy downregulate cytokine storm COVID-19 zebrafish model. RT-qPCR analyses...
Summary Establishing new experimental animal models to assess the safety and immune response antigen used in development of COVID-19 vaccine is an imperative issue. Based on advantages using zebrafish as a model research, herein we suggest doing this test putative candidates study against virus. We produced recombinant N-terminal fraction Spike SARS-CoV-2 protein injected it into adult female zebrafish. The specimens generated humoral immunity passed antibodies eggs. However, they presented...
Several multiplex approaches for the simultaneous detection of pathogens in food have been developed recent years, but use a single enrichment medium remains problem. In this study, six broths (five non-selective media, tryptic soy broth (TSB), brain heart infusion (BHI), buffered peptone water (BPW), universal pre-enrichment (UPB), no. 17 broth, and selective, Salmonella Escherichia Listeria (SEL)), were studied E. coli O157:H7, spp., L. monocytogenes, to validate suitable be used methods....
Na Atenção Primária à Saúde (APS), o trabalho em equipe é fundamental para um cuidado integral todos os níveis do Sistema Único de (SUS). O profissional farmacêutico uma das profissões que pode integrar essas equipes multiprofissionais. Este estudo tem como objetivo analisar a inserção na atenção primária, identificando suas experiências, atribuições e desafios. Trata-se revisão integrativa da literatura, exploratória descritiva, com levantamento 11 artigos científicos publicados entre 2017...
Reduced sensitivity to thyroid hormones (RSTH) is a rare disease that affects about 3,000 individuals, belonging 1,000 families. It results from reduced intracellular action of (TH) genetically determined and manifests as persistent hyperthyroxinemia with non-suppressed thyroid-stimulating hormone (TSH). We describe 67-years old, Caucasian woman, past history subtotal thyroidectomy due diffuse goiter, who presents recurrence goiter. Although she clinically euthyroid, laboratory evaluation...
Hyperthyroidism is a risk factor for reduced bone mineral density (BMD) and osteoporotic fractures. Vertebral fracture assessment (VFA) by dual-energy X-ray absorptiometry (DXA) radiological method of visualization the spine, which enables patient comfort radiation exposure.This study was carried out to evaluate BMD prevalence silent vertebral fractures in young men with hyperthyroidism.We conducted cross-sectional group Portuguese aged up 50 years matched hyperthyroidism (n=24) control...
SARS-CoV-2 diagnostic tests have become an important tool for pandemic control. Among the alternatives COVID-19 diagnosis, antigen rapid (Ag-RDT) are very convenient and widely used. However, as variants may continuously emerge, replacement of reagents be required to maintain sensitivity Ag-RDTs. Here, we describe development validation Ag-RDT during outbreak Omicron variant, including characterization a new monoclonal antibody (anti-DTC-N 1B3 mAb) that recognizes Nucleocapsid protein (N)....
The presence of chronic lymphocytic leukaemia (CLL) cells in the thyroid gland is most likely due to a secondary involvement by systemic disease. reported incidence CLL involving extremely low, representing about 3–4% all lymphoproliferative neoplasm. We report rare case presenting initially gland. Systemic disease was detected as result investigation. An 85 years old woman, with multinodular goiter without adenophaties, referred our department, carrying fine needle aspiration biopsy (FNAB)...
The literature review provides information on the major calcium-regulating hormones and their role in regulation of bone remodeling. These processes are also influenced by sex steroids, growth hormone, insulin, cortisol, thyroid various local factors. In this regard, osteopenia osteoporosis closely linked to a number endocrine diseases, some which common (diabetes mellitus, hyperthyroidism), others — quite rare (endogenous hypercortisolism). Osteoporosis associated with diabetes, steroid...
In urban centers, the most important genera of termite pests are Cryptotermes (Kalotermitidae), Coptotermes (Rhinotermitidae) and Nasutitermes (Termitidae). Results obtained with plant extracts for termites control show that they may be a potential cheap method. Brazil, phytopharmacological collection is still understudied, more investigations on biological proprieties forests species present toxicity to xylophagous insects needed. The goal this paper test antifeedant repellent Tachigali...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
The gene TAS2R38 single nucleotide polymorphisms (SNPs-P49A, A262V and V296I) can condition bitter tasting by PAV (proline–alanine–valine) non-bitter-tasting AVI (alanine–valine–isoleucine) homozygosity. We evaluated this association with thyroid function, metabolism anthropometry parameters determined by: Endpoint analysis (SNPs); DXA (fat mass-%, total fat mass—kg, lean mass—kg); Standard methods (lipid parameters, HbA1c-%, glycemia—mg/dL, insulinemia—µIU/mL, HOMA-IR, uricemia—mg/dL,...
The 2018 published World Health Organisation (WHO) Europe physical activity factsheet reports, specify agreed targets for and articulate the need to improve education of medical doctors healthcare practitioners in order increase reduce sedentary time people at risk and/or living with Noncommunicable Diseases (NCDs). Given dearth relevant initiatives continuous participation towards better health management NCDs, aim this study is embed undergraduate curricula future frontline professionals...