- Vitamin D Research Studies
- Nutritional Studies and Diet
- Bone health and osteoporosis research
- Vitamin C and Antioxidants Research
- Trace Elements in Health
- Diet and metabolism studies
- Intensive Care Unit Cognitive Disorders
- Nutrition and Health in Aging
- Obesity, Physical Activity, Diet
- Sports Performance and Training
- COVID-19 Clinical Research Studies
- Heavy Metal Exposure and Toxicity
- Exercise and Physiological Responses
- Muscle metabolism and nutrition
- S100 Proteins and Annexins
- Plant Micronutrient Interactions and Effects
- Adipokines, Inflammation, and Metabolic Diseases
- Magnesium in Health and Disease
- Birth, Development, and Health
- Body Composition Measurement Techniques
- Thyroid Cancer Diagnosis and Treatment
- Adipose Tissue and Metabolism
- Pregnancy and Medication Impact
- Adrenal Hormones and Disorders
- Stress Responses and Cortisol
Universidad de Granada
2020-2025
Institut d'Investigació Sanitària Pere Virgili
2025
Centro de Investigación Biomédica en Red
2025
Universitat Rovira i Virgili
2025
Instituto de Salud Carlos III
2025
Universidad de La Rioja
2025
Antioxidant defenses in biological systems ensure redox homeostasis, regulating baseline levels of reactive oxygen and nitrogen species (ROS RNS). Oxidative stress (OS), characterized by a lack antioxidant or an elevation ROS RNS, may cause modification biomolecules, being primarily absorbed proteins. As result both genome environment interactions, proteomics provides complete information about cell’s proteome, which changes continuously. Besides measuring protein expression levels, can also...
Importance Understanding the effects of diet and physical activity on bone health may help to mitigate concomitant weight loss– age-related deterioration. Objective To evaluate a weight-loss lifestyle intervention mineral density (BMD), content (BMC), low BMD prevalence. Design, Setting, Participants The 3-year, parallel-group Prevención con Dieta Mediterránea–Plus (PREDIMED-Plus) randomized clinical trial was conducted at recruiting centers in Spain from October 2013 December 2016. Men...
α-Klotho protein is a powerful predictor of the aging process and lifespan. Although lowered circulating soluble levels have been observed in aged non-healthy individuals, no specific reference values across wide range ages sex using an enzyme-linked immunosorbent assay (ELISA) are available for larger cohorts healthy individuals. The present analytical cross-sectional study was aimed to establish serum adults by age groups. A total 346 (59% women) individuals from 18 85 years were...
Administering N-acetylcysteine (NAC) could counteract the effect of free radicals, improving clinical evolution patients admitted to Intensive Care Unit (ICU). This study aimed investigate and biochemical effects administering NAC critically ill with COVID-19. A randomized controlled trial was conducted on ICU (n = 140) COVID-19 divided into two groups: treated (NAC-treated group) without treatment (control group). administered as a continuous infusion loading dose maintenance during period...
The present study aimed to 1) investigate the consumption of Sports Supplements (SSs) among female elite football players, 2) evaluate influence age on SS consumption, and 3) determine relationship between SSs dietary choices players.
Abstract Background Steroid hormones are key mediators of adaptative responses to exercise, a stimulus that may concurrently affect their blood concentrations. However, the chronic endocrine adaptations and whether these potential changes dependent on exercise intensity remain undetermined. Moreover, it is also unknown if exercise‐induced effects steroid hormonal status related participant' sex. Methods This study aimed investigate 24‐week supervised concurrent training intervention in...
Abstract Background Soluble Alpha-Klotho (S-αklotho) protein and 25-Hydroxyvitamin D (25-OH-D) have emerged as potential modulators for activating recruiting Brown Adipose Tissue (BAT). The present study aimed to investigate whether circulating S-αklotho 25-OH-D levels are related BAT volume, 18 Fluorine-Fluorodeoxyglucose ( F-FDG) uptake, radiodensity in young healthy adults. Methods A total of 128 participants (68% women) aged 18–25 years old participated this cross-sectional study. Serum...
The present study explores how fatigue evolves throughout a single-day national badminton tournament involving five consecutive matches, by examining subjective and objective metrics. Eleven U-17 athletes (14-16 years old; 45% women) were evaluated in real competition using assessments, including the rate of perceived exertion (RPE), session RPE (sRPE), muscular visual analog scale (MFVAS), total quality recovery test (TQR), as well measures like countermovement jump peak height (CMJh), drop...
In this study, we measured the dose-response effect of a 24-week concurrent training (CT) intervention on low-grade systemic inflammation biomarkers in sedentary young healthy adults. A total 100 untrained participants were randomized to (1) no exercise (control group, n = 35), (2) aerobic + resistance at moderate intensity (exercise-moderate group; 33), or (3) CT vigorous (exercise-vigorous 32). Serum concentrations C-reactive protein (CRP), interleukin-6 (IL-6), IL-7, IL-8, and IL-10,...
Abstract The protective role of dietary vitamin D intake on cognitive function is interest, but evidence remains inconsistent. We aimed to evaluate the association between and 2-year changes in older adults at risk decline. This longitudinal study comprised 5454 individuals (aged 55–75 years men 60–75 women) who exhibited overweight/obesity metabolic syndrome. Data was assessed using a validated 143-item food frequency questionnaire. Cognitive through five composite scores derived from...
Menopause is a stage of hormonal imbalance in women which, addition to other physiopathological consequences, poses risk deficiency key micronutrients such as magnesium and vitamin D. A study was made the influence intervention upon D status postmenopausal population from province Granada (Spain). Fifty-two healthy between 44-76 years age were included. Two randomized groups-placebo (500 mg/day)-were treated during eight weeks. Nutrient intake assessed using questionnaires based on 72-h...
Vitamin D is a micronutrient that plays key role in phosphocalcic metabolism. The postmenopausal population presents risk of deficiency this vitamin due to hormonal alterations which, the case obesity, would be exacerbated. objective was assess status and determine relationship 25-hydroxivitamin [25(OH)D] its metabolites with anthropometric parameters. study included 78 healthy women aged from 44 76. nutrient intake assessment carried out using 24 h reminder (R24h). 25(OH)D analyzed...
The aim of this study was to investigate the response interleukin-6 (IL-6) during first few hours a patient's stay in Intensive Care Unit (ICU) sample critically ill patients with septic shock, compared healthy subjects as controls. Additionally, examined association IL-6 morbidity and mortality these patients, well its relationship biomarkers such lactic acid, C-reactive protein (CRP) procalcitonin (PCT).
Postmenopausal aging has become relevant for understanding health during the transition life stages-the process being involved in several disturbances of human condition. The present study aimed to investigate relationship between postmenopausal and sociodemographic, anthropometric, body composition, nutritional, biochemical (i.e., protein lipid profiles, phosphorous-calcium metabolism, antioxidant status) factors women. This cross-sectional enrolled 78 healthy women (44-76 years)....
Background and aims: Vitamin D inadequacy may be involved in the mechanisms of SARS-CoV-2 infection potential risk factors for disease propagation or control coronavirus 2019 (COVID-19). This study assessed a short-term evolution vitamin status its influence upon different clinical parameters critically ill patients with COVID-19. Methods: A prospective analytical which 37 volunteers between 41 71 years age COVID-19 were evaluated at baseline three days intensive care unit (ICU) stay....
This study evaluated the clinical and nutritional status, evolution over three days, relationship between nutritional, inflammatory, parameters of critically ill patients with COVID-19. A longitudinal was conducted in Intensive Care Unit Virgen de las Nieves University Hospital Granada (Spain). The population comprised a positive polymerase chain reaction test for COVID-19 presenting critical involvement. Clinical outcomes were collected, inflammatory (albumin, prealbumin, transferrin,...