Sang Chan Kim

ORCID: 0000-0003-0515-0764
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About
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Research Areas
  • Pharmacological Effects of Natural Compounds
  • Healthcare and Venom Research
  • Ginseng Biological Effects and Applications
  • Natural product bioactivities and synthesis
  • Food Quality and Safety Studies
  • Genomics, phytochemicals, and oxidative stress
  • Phytochemistry and Biological Activities
  • Drug-Induced Hepatotoxicity and Protection
  • NF-κB Signaling Pathways
  • Traditional Chinese Medicine Studies
  • Autophagy in Disease and Therapy
  • Acupuncture Treatment Research Studies
  • Neurotransmitter Receptor Influence on Behavior
  • Liver Disease Diagnosis and Treatment
  • Ginger and Zingiberaceae research
  • Gastrointestinal motility and disorders
  • Traditional Chinese Medicine Analysis
  • Pain Mechanisms and Treatments
  • Metabolism, Diabetes, and Cancer
  • Ion Channels and Receptors
  • Stress Responses and Cortisol
  • Immune Response and Inflammation
  • Sleep and Wakefulness Research
  • Phytochemistry and biological activity of medicinal plants
  • Peroxisome Proliferator-Activated Receptors

Daegu Haany University
2015-2024

Brigham Young University
2014

Harbin Medical University
2014

Fourth Affiliated Hospital of Harbin Medical University
2014

Mudanjiang Medical University
2014

Dunsan Korean Medicine Hospital
2014

Catholic University of Daegu
2013

Jacksonville College
2011

Mayo Clinic in Florida
2011

WinnMed
2011

The PI3K/Akt and mTOR signaling pathways are important for cell survival growth, they highly activated in cancer cells compared with normal cells. Therefore, these targets inducing death. dual inhibitor NVP-BEZ235 completely inhibited both pathways. However, had no effect on death human renal carcinoma Caki We tested whether combined treatment natural compounds could induce Among several chemopreventive agents, curcumin, a biologically active compound that is extracted from the rhizomes of...

10.1371/journal.pone.0095588 article EN cc-by PLoS ONE 2014-04-17

Moutan Cortex (MCE) has been used in traditional medicine to remove heat from the blood, promote blood circulation and alleviate stasis. This study was conducted evaluate effects of MCE on regulatory mechanisms cytokines nitric oxide (NO) involved immunological activity Raw264.7 cells. Cells were pretreated with methanolic extracts MCE, further cultured for an appropriate time after lipopolyssacharide (LPS) addition. During entire experimental period, 0.1 0.3 mg ml(-1) had no cytotoxicity....

10.1093/ecam/nel093 article EN cc-by Evidence-based Complementary and Alternative Medicine 2006-10-13

Korean ginseng (Panax C.A. Meyer) has been used as a botanical medicine throughout the history of Asian traditional Oriental medicine. Formulated red (one form ginseng) shown to have antioxidant and chemopreventive effects.This study investigated cytoprotective effects mechanism action extract (RGE) against severe ROS production mitochondrial impairment in cytotoxic cell model induced by AA + iron.RGE protected HepG2 cells from iron-induced cytotoxicity preventing induction dysfunction...

10.1186/1472-6882-13-64 article EN cc-by BMC Complementary and Alternative Medicine 2013-03-18

Laminaria japonica has frequently been used as a food supplement and drug in traditional oriental medicine. Among the major active constituents responsible for bioactivities of L. japonica, fucoxanthin (FX) considered potential antioxidant. This study was conducted to examine effects extract (LJE) or FX against oxidative stress on hepatocytes elucidate overall their cellular mechanisms effects. We constructed an vitro model with treatment arachidonic acid (AA) + iron HepG2 cells stimulate...

10.1186/s12906-018-2164-2 article EN cc-by BMC Complementary and Alternative Medicine 2018-03-20

Liquiritigenin (LQ), an active component of licorice, has inhibitory effect on LPS-induced nitric oxide synthase expression. This study investigated the effects LQ choleresis, expression hepatic transporters and phase-II enzymes, fulminant hepatitis. The choleretic pharmacokinetics its glucuronides were monitored in rats. After intravenous administration LQ, total area under plasma concentration-time curve glucuronyl metabolites was greater than that plasma, which accompanied elevations bile...

10.1152/ajpgi.90524.2008 article EN AJP Gastrointestinal and Liver Physiology 2008-12-13
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