A5073014067- HIV/AIDS Research and Interventions
- Mosquito-borne diseases and control
- Viral Infections and Vectors
- HIV Research and Treatment
- Hepatitis B Virus Studies
- Hepatitis C virus research
- HIV/AIDS oral health manifestations
- Pleural and Pulmonary Diseases
- Leptospirosis research and findings
- HIV/AIDS drug development and treatment
- Amoebic Infections and Treatments
- Science and Education Research
- Fungal Infections and Studies
- HIV-related health complications and treatments
- Syphilis Diagnosis and Treatment
- SARS-CoV-2 and COVID-19 Research
- Hepatitis Viruses Studies and Epidemiology
- Biosensors and Analytical Detection
- Liver Disease Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Orthopedic Infections and Treatments
- Immune Cell Function and Interaction
- Malaria Research and Control
- Hemophilia Treatment and Research
- Research on Leishmaniasis Studies
Universidade de Fortaleza
2016-2025
Universidade Federal do Ceará
2014-2023
Unifor
2022
Universidade de São Paulo
2001-2020
Instituto de Medicina Tropical
2020
Secretaria da Saúde
2018-2020
Universidade Estadual do Ceará
2020
Hospital Geral de Fortaleza
2020
Fundação Oswaldo Cruz
2019
Universidade Brasil
2005-2008
We describe six cases of healthcare professionals in Brazil who recovered but again presented symptoms consistent with COVID-19, new positive reverse transcription (RT)-PCR test results. The reported herein symptom onset between March 16, 2020 and April 9, 2020. All were health (four medical doctors), five female, a median age 43.5 years, three had comorbidities. patients confirmed for SARS-CoV-2 detection by RT-PCR naso and/or oropharyngeal swab samples. Among the cases, (50%) underwent...
Visceral Leishmaniasis is the most severe form of disease caused by Leishmania donovani complex, with significant morbidity and mortality in developing countries. Worse outcomes occur among HIV-positive individuals coinfected Leishmania. It unclear, however, if there are differences on presentation between patients or without HIV coinfection.We reviewed medical records from adult treated at a reference healthcare center Fortaleza - Ceará, Brazil, July 2010 to December 2013. Data...
Background/Objectives: Guillain–Barré syndrome (GBS) is a neurological disease that affects the peripheral nerves. The exact cause of this condition still uncertain, but cross-reactivity between pathogen antigens and nervous tissue may play crucial role in pathogenesis. Roseolovirus humanbeta6 (HHV-6), neurotropic virus with latency capacity, be considered significant candidate for triggering or worsening conditions. In study, we aimed to investigate detection HHV-6 CNS from GBS patients. Of...
Background: HBV (Hepatitis B Virus) and HCV C infections are more prevalent in vulnerable populations than the general population. The objective of this study was to investigate prevalence infection HIV-positive patients (GI), chronic renal failure (CRF) (GII) coagulation disorder individuals (GIII). Methods: A cross-sectional conducted from June 2014 March 2015. Serum samples were tested for markers hepatitis by enzyme-linked immunosorbent assay (ELISA). Sociodemographic, epidemiological,...
Reverse transcription loop-mediated isothermal amplification (RT-LAMP) is a rapid method that can replace RT-qPCR. A simple molecular assay for SARS-CoV-2 RNA detection in gold-standard diagnosis through swabs and alternative specimens such as saliva could be helpful promoting genomic surveillance. multicenter study was conducted to evaluate the RT-LAMP an of lineages swab samples. total 350 from individuals with (n = 276) or without 74) COVID-19 tested by RT-qPCR were collected. Paired also...
SUMMARY Leptospirosis is a febrile disease with typically underestimated global incidence, especially in regions where dengue endemic. Therefore, it difficult to accurately determine the number of leptospirosis cases these areas, which contributes significant under-reporting this disease. In study, we estimated possible among dengue-like that were reported during 2008, 2010, and 2012 city Fortaleza, northeast Brazil. Patients evaluated for using immunoenzymatic tests IgM antibodies specific...
Point of care testing (POCT) has been used for hepatitis B and C diagnosis in general population, but little is known about the influence clinical conditions accuracy these assays. This study aims to evaluate performance POCTs detection virus surface antigen (HBsAg) antibodies Hepatitis Virus (anti-HCV) Chronic Kidney Disease (CKD) patients.A total 286 subjects were included this study. HBsAg anti-HCV detected using commercial EIAs four POCTs: (WAMA Imuno-Rápido VIKIA HBsAg) (DOLES HCV teste...
Dengue is endemic in Brazil. The dengue surveillance system's reliance on passive reporting may underestimate disease incidence and cannot detect asymptomatic/pauci-symptomatic cases. In this 3-year prospective cohort study (NCT01391819) 5- to 13-year-old children from nine schools Fortaleza (N = 2,117), we assessed virus (DENV) infection seroprevalence by IgG indirect ELISA at yearly visits through active enhanced surveillance. Real-time quantitative polymerase chain reaction (RT-qPCR) DENV...
From 2013 to 2015, sanitary authorities reported an increased incidence of Guillain-Barré syndrome (GBS) associated with Zika virus (ZIKV) in French Polynesia, Caribbean, and Brazil.1–3 After the end ZIKV epidemics, GBS cases where still above usual limits countries arrival chikungunya (CHIKV) was also a concern.3 The authors would like thank Professor Steven S. Witkin from Weill Cornell Medicine for constructive comments kindness editing manuscript, Vânia Maria Alves de Araujo Hospital...
Antiretroviral resistance mutations (ARM) are one of the major obstacles for pharmacological human immunodeficiency virus (HIV) suppression. Plasma HIV-1 RNA from 306 patients on antiretroviral therapy with virological failure was analyzed, most them (60%) exposed to three or more regimens, and 28% have started before 1997. The common regimens in use at time genotype testing were AZT/3TC/nelfinavir, 3TC/D4T/nelfinavir AZT/3TC/efavirenz. majority ARM occurred protease (PR) gene residue L90...
The aim of this study was to investigate HIV-1 molecular diversity and the epidemiological profile HIV-1-infected patients from Ribeirão Preto, Brazil. A nested PCR followed by sequencing a 302-base pair fragment env gene (C2-V3 region) performed in samples HIV-1-positive patients. total 45 sequences were aligned with final manual adjustments. phylogenetic analyses showed higher prevalence subtype B studied population (97.8%) only one sample yielding an F1 subtype. viral genotyping...
BACKGROUNDTo achieve the elimination of hepatitis B and C, there is an urgent need to develop alternative strategies increase access diagnosis, particularly among key populations such as people living with human immunodeficiency virus (HIV), individuals coagulopathies chronic kidney disease (CKD) patients. AIM
While human immunodeficiency virus (HIV)-1 chemokine co-receptors 5 tropism and the GWGR motif in envelope third variable region (V3 loop) have been associated with a slower disease progression, their influence on antiretroviral response remains unclear. The impact of baseline V3 characteristics treatment was evaluated randomised, double blind, prospective cohort study patients initiating highly active therapy lopinavir or efavirenz plus azithothymidine/3TC (1:1) over 48 weeks. Similar...
AIMTo evaluate viral hepatitis knowledge among individuals from different resource areas and health conditions to identify possible gaps.
HIV patients frequently have opportunistic oesophageal infections. We report Haemophilus ducreyi genetic material detected by polymerase chain reaction in biopsies of lesions three HIV-1-infected patients. This finding may be an indication its aetiopathological role
Parvovirus B19 (B19V) infection is commonly acute and self-limited, but in chronic kidney disease (CKD) patients under dialysis treatment, this could increase susceptibility to anemia. The aim of study was evaluate the frequency risk B19V among Brazilian CKD dialysis.A conducted 221 a control group 142 blood donors. evaluated serum samples by real-time PCR, ELISA (anti-B19V IgM IgG).B19V DNA detected 65% (145/221) patients, which significantly higher (p < 0.001) than donors (6.3%)....
Introduction: Dengue and leptospirosis are two febrile illnesses of great clinical epidemiological importance in Brazil. Their significant degree symptomatic similarity makes diagnosis difficult.Objective: To diagnose differentially patients with clinically suspected dengue.Materials methods: In this study, 86 dengue underwent virological serological diagnostic evaluations for (reverse transcriptase polymerase chain reaction, NS1 immunochromatographic test, enzyme-linked immunosorbent assay,...
Objective: To determine the prevalence of patients at risk developing HIV-associated neurocognitive disorder (HAND) and identify factors possibly associated with its occurence. Methods: Quantitative cross-sectional study conducted Specialized Care Service (Serviço de Atendimento Especializado - SAE) for HIV/Aids Integrated Medical Center (Núcleo Médico Integrado NAMI) University Fortaleza (Universidade UNIFOR), Fortaleza, Ceará, Brazil. We reviewed medical records all 249 that started...