A5073508651- Catalytic C–H Functionalization Methods
- Sulfur-Based Synthesis Techniques
- Synthesis and Catalytic Reactions
- Catalytic Alkyne Reactions
- Cyclopropane Reaction Mechanisms
- Radical Photochemical Reactions
- Crystallization and Solubility Studies
- Asymmetric Hydrogenation and Catalysis
- Catalytic Cross-Coupling Reactions
- X-ray Diffraction in Crystallography
- Medicinal Plants and Neuroprotection
- Nanoparticles: synthesis and applications
- Synthesis of Organic Compounds
- Healthcare and Environmental Waste Management
- Educational Reforms and Innovations
- Fluorine in Organic Chemistry
- Chemical Synthesis and Reactions
Shandong University
2022
Zhejiang University of Technology
2018-2022
Third Affiliated Hospital of Inner Mongolia Medical College
2022
Inner Mongolia Medical University
2022
Hangzhou Xixi hospital
2018-2020
A visible-light-induced photocatalyst-free three-component radical cascade bicyclization has been achieved to obtain diverse difluoroamidosulfonylated dihydrobenzofurans in moderate good yields. This protocol avoids potential toxicity and the tedious removal procedure for photocatalysts also features mild reaction conditions a functional group tolerance. Moreover, mechanistic investigations reveal formation of charge-transfer complex involvement an intramolecular 1,5-hydrogen atom transfer...
An efficient Ru-catalyzed C6 site-selective amidation of 2-pyridones has been accomplished with dioxazolone under mild conditions.
Rh(<sc>iii</sc>)-catalyzed coupling of phenylhydrazines with 1-alkynylcyclobutanols was realized through a hydrazine-directed C–H functionalization and [4+1] annulation pathway.
Abstract A formation of fused tricyclic [1,3]oxazino[3,4‐ a ]indol‐1‐ones and dihydropyrimido[1,6‐ ]indol‐1(2 H )‐ones via Rh(III)‐catalyzed [3+3] or [4+2] annulation N ‐methoxy‐1 ‐indole‐1‐carboxamides with sulfoxonium ylides has been developed. These selective reactions were carried out by switching the additives notable features this protocol low catalyst loading broad substrate scope providing corresponding products in up to 99% yields. magnified image
Abstract An iron‐catalyzed three‐component cyanoalkylsulfonylation of 2,3‐allenoic acids, K 2 S O 5 , and the ring‐opening cyclobutanone oxime esters is described. The radical tandem cyclization route allows access to diverse cyanoalkylsulfonylated butenolides in moderate good yields under mild conditions. Moreover, products are further converted, offering corresponding derivatives. magnified image
Abstract A mild and safe photochemical methodology has been developed to access difluoroamidosulfonylated dioxodibenzothiazepines via three‐component radical bicyclization cascades. This photocatalyst‐free transformation avoids cumbersome photocatalyst removal procedure potential toxicity. Mechanistic experiments reveal the generation of an electron donor‐acceptor (EDA) complex in reaction process. Moreover, synthetic value protocol is further demonstrated by gram‐scale reaction, conversion...
A novel palladium-catalyzed [2 + 2 1] annulation of alkyne-tethered aryl iodides with diaziridinone was developed, leading to the formation 3,4-fused tricyclic indoles. From a mechanistic standpoint, fused indole scaffolds involved C,C-palladacycles, which were synthesized through intramolecular reaction halides and alkynes. The cascade described herein could be carried out broad range substrates provided various indoles yields up 98%.
A novel Rh(III)-catalyzed annulation of phthalazinones or pyridazinones with various allenes was developed, leading to the formation indazole derivatives bearing a quaternary carbon in moderate good yields. The targeted products were synthesized via sequential C-H activation and olefin insertion, followed by β-hydride elimination intramolecular cyclization. synthetic protocol proceeded efficiently broad functional group tolerance, high atom efficiency Z-selectivity. practicability this...
The efficient synthesis of diverse 3‐alkylthiochromone species through radical‐triggered cyclization methylthio‐substituted alkynones is reported. This metal‐free protocol compatible with a wide variety radical donors under mild conditions, thus enabling the various 3‐alkylthiochromones.
A rhodium( iii )-catalyzed [4 + 1] spiroannulation of N -aryl phthalazine-diones (pyridazine-diones) with diazo compounds to construct spirocyclic indazole derivatives diverse structures is described.
An efficient Rh-(III)-catalyzed C-H functionalization of N-ethoxybenzamides with 1-alkynylcyclobutanols has been developed. Isoquinolone derivatives have successfully synthesized through [4 + 2] annulation and ring opening reaction under mild conditions. The advantages this protocol include broad substrate scope good to excellent yields.
We investigated a novel Cu-catalyzed annulation of 2,3-allenoic acids with diphenylphosphine oxide, leading to the formation 4-phosphate butenolides in up 88% yield. The C–P bond provides new avenues for functionalization different furan-2(5H)-ones, favorable features such as suitable functional group tolerance and mild synthesis conditions.
Abstract This work showed the preparation of Copper oxide nanoparticles (CuO NPs) from leaf extract Cinnamomum camphora (C.camphora) by a green synthetic method. To prepare CuO NPs, about 10 ml 0.01 M copper sulphate and 30 C.camphora were mixed heating for 60 min at temperature 80 °C. Various techniques such as x-ray diffraction analysis (XRD), Energy-dispersive spectroscopic (EDS), Fourier-transform infrared spectroscopy (FTIR), dynamic light scattering (DLS), UV–vis (UV–vis) Transmission...
In view of the problems existing in teaching instrumental analysis for undergraduate students, such as outdated materials, course contents, lack examination and evaluation standards, we summarize current materials systems related to chemistry some representative foreign universities.Through comparative analysis, hope that this paper can provide a powerful reference our future construction improvement content reform assessment methods.