A5065486126- Catalytic C–H Functionalization Methods
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Catalytic Alkyne Reactions
- Chemical Synthesis and Reactions
- Catalytic Cross-Coupling Reactions
- Asymmetric Hydrogenation and Catalysis
- Sulfur-Based Synthesis Techniques
- Synthesis and Catalytic Reactions
- Synthetic Organic Chemistry Methods
- Crystallography and molecular interactions
- Cyclopropane Reaction Mechanisms
- Chemical Synthesis and Analysis
- Organometallic Complex Synthesis and Catalysis
- Oxidative Organic Chemistry Reactions
- Carbon dioxide utilization in catalysis
- Synthesis and Characterization of Pyrroles
- Multicomponent Synthesis of Heterocycles
- Organoboron and organosilicon chemistry
- Synthesis and Biological Evaluation
- Asymmetric Synthesis and Catalysis
- Synthesis of Indole Derivatives
- Polyoxometalates: Synthesis and Applications
- Fluorine in Organic Chemistry
- Click Chemistry and Applications
Tsinghua University
2016-2025
Xinjiang University
2022-2025
Hebei Science and Technology Department
2013-2014
Nankai University
2009-2013
McGill University
2012
Tokyo Institute of Technology
1996-2009
Sinopec (China)
2009
Ministry of Education of the People's Republic of China
2006
National Institute of Advanced Industrial Science and Technology
2002-2006
Tokyo University of Science
2001-2006
Under copper-free conditions and with Cs2CO3 as a base, PdCl2(PCy3)2 showed high catalytic activity for cross-coupling of electron-rich, electron-neutral, electron-deficient aryl chlorides variety terminal alkynes in DMSO at 100−120 °C affording internal arylated good to excellent yields.
An efficient one-pot synthesis of isoquinolines and heterocycle-fused pyridines by three-component reaction aryl ketones, hydroxylamine, alkynes is developed. The involves condensation ketones rhodium(III)-catalyzed C-H bond activation the in situ generated ketone oximes, cyclization with internal alkynes. This protocol enables rapid assembly multisubstituted as well γ-carbolines, furo[2,3-c]pyridines, thieno[2,3-c]pyridines, benzofuro[2,3-c]pyridines from readily available substrates.
Abstract An efficient, practical, and external‐oxidant‐free indole synthesis from readily available aryl hydrazines was developed, by using hydrazone as a directing group for Rh III ‐catalyzed CH activation alkyne annulation. The formed in situ condensation of CO source, whereas its NN bond served an internal oxidant, which we termed it auto‐formed auto‐cleavable (DG auto ). This method needs no step pre‐installation post‐cleavage the group, making quite easily scalable approach to access...
A concise and straightforward strategy to construct a xanthone skeleton via an intramolecular cross-dehydrogenative coupling (CDC) of 2-aryloxybenzaldehydes has been developed. The reaction proceeded smoothly without any need preactivation the aldehyde group. It can tolerate various functional groups provides applicable protocol wide range derivatives.
Hole transport materials (HTMs) with high hole mobility, good band alignment and ease of fabrication are highly desirable for perovskite solar cells (PSCs). Here, we designed synthesized novel organic HTMs, named T3, which can be in yields commercially available materials, featuring a substituted pyrrole core triphenylamine peripheral arms. The capability functionalization the final synthetic step provides an efficient way to obtain variety T3-based HTMs tunable energy levels other...
DMF (N,N-dimethylformamide)/KOH was found to be an efficient hydrogen source in the Pd(OAc)2-catalyzed transfer semihydrogenation of various functionalized internal alkynes afford cis-alkenes good high yields with excellent chemo- and stereoselectivity. This catalytic process also applied synthesis analogues combretastatin A-4.
Bismuth(III) compounds (BiX3, X = Cl, Br, NO3 and OTf etc.) are moisture- air-tolerant Lewis acids, which have been widely applied as green catalyst in diverse organic synthesis the past few years. This review illustrates significant advances this field over recent five years, mainly focuses on bismuth-catalyzed formation of carbon-carbon, carbon-nitrogen, carbon-sulfur bonds, well oxidation reaction, protection deprotection alcohols carbonyl compounds, reactions aqueous media. Keywords:...
Abstract [Ru 3 (CO) 12 ]‐catalyzed transfer semihydrogenation of various functionalized diaryl alkynes with N , ‐dimethylformamide (DMF) and water as hydrogen source affords cis ‐ trans ‐stilbenes. The stereodivergent approach can be switched by the use acetic (HOAc) or trifluoroacetic (TFA) acid additives. catalytic processes applied to synthesis analogues natural products such ‐combretastatin A‐4 ‐resveratrol.
π-Extension of 2-aryl-phenanthroimidazoles via rhodium(III)-catalyzed C-H activation and alkyne annulation is developed. This method enables rapid, practical modular assembly diverse ring-fused phenanthroimidazoles, including an unusual rearrangement product using aryl-alkyl asymmetric a thiophene fused which could serve as Fe(3+) fluorescent probe. The feasibility the one-pot synthesis ruthenium(II)-catalyzed versions this reaction was also verified.
An efficient, one-pot synthesis of multisubstituted 2-aminoquinolines from 1-aryl tetrazoles and internal alkynes has been developed. The reaction involves cyclization with via rhodium(III)-catalyzed double C-H activation copper(II)-mediated denitrogenation.
One drop is enough to switch from hydropalladation phosphinylpalladation. If one of diphenylphosphinic acid added for the hydrophosphinylation alkynes with diphenylphosphane oxide, there a reversal in regioselectivity (as shown below).
In the presence of a catalytic amount Re(CO)(5)Br, coupling epoxides with supercritical CO(2) without an organic solvent at 110 degrees C has afforded cyclic carbonates in good to excellent yields.
Abstract In the presence of BiCl 3 , hydroarylation styrenes with electron‐rich arenes afforded Markovnikov adducts selectively in good to high yields. Under arene‐free conditions, intermolecular α‐substituted and subsequent intramolecular produced cyclic dimers (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)
Recent advances on the synthesis of six-membered carbo- and heterocyclic compounds including functionalized benzenes, 1,3- cyclohexadienes, pyridines, pyridones, pyranones, coumarins isocoumarins via cycloaddition reaction alkynes are reviewed. Special attention is paid to atom-economic controllable chemo- regioselective reactions, which currently extremely attractive methodologies in organic synthesis. Keywords: Alkynes, cycloaddition, carbocycles, heterocycles
Abstract CuCl with the use of a catalytic amount piperidine as additive shows high activity for oxidative homocoupling reactions terminal alkynes in toluene at 60 °C air to afford 1,3‐diynes yields. Copyright © 2009 John Wiley & Sons, Ltd.
By DFT calculation, we found that acid-catalyzed carboxylic acid esterification and ester hydrolysis are brief two-step reactions. First, the hydroxyl-oxygen or alkyl-oxygen is protonated, which generates a highly active acylium ion. The protonation requires an activation energy (Ea) of 4-10 kcal mol(-1), rate-controlling step hydrolysis. Sequentially, ion spontaneously reacts with two alcohol water molecules to form neutral product molecule; this trimolecular reaction. intermediate shared...
[reaction: see text] Bi(NO(3))(3).5H(2)O was used as an efficient nitrating reagent in the nitration of phenolic compounds to give nitrated phenols good high yields. The reaction proceeded smoothly by grinding 1 equiv phenol, 2-methylphenol, 4-methylphenol, or 4-chlorophenol and Bi(NO(3))(3).5H(2)O, other could be performed acetone at ambient temperature (22-30 degrees C).
The addition reaction of chloroacetyl chloride derivatives with terminal alkynes was found to be catalyzed by Rh(acac)(CO)(AsPh(3)) afford (Z)-1,4-dichloro-3-buten-2-one derivatives, which displayed diverse reactivities in synthetic elaboration.