A5100456883- Electrochemical Analysis and Applications
- Electrochemical sensors and biosensors
- Pelvic floor disorders treatments
- Analytical Chemistry and Sensors
- Conducting polymers and applications
- Graphene and Nanomaterials Applications
- Analytical Chemistry and Chromatography
- Analytical Methods in Pharmaceuticals
- Carbon and Quantum Dots Applications
- Biosensors and Analytical Detection
- Luminescence and Fluorescent Materials
- Quinazolinone synthesis and applications
- Ginger and Zingiberaceae research
- Photochromic and Fluorescence Chemistry
- Enhanced Recovery After Surgery
- Nanoplatforms for cancer theranostics
- Advanced Welding Techniques Analysis
- Ionic liquids properties and applications
- Metal and Thin Film Mechanics
- Pregnancy-related medical research
- Pickering emulsions and particle stabilization
- Combustion and Detonation Processes
- Aluminum Alloy Microstructure Properties
- Dielectric materials and actuators
- Urinary Bladder and Prostate Research
NorthShore University HealthSystem
2024-2025
Weatherford College
2023
Sookmyung Women's University
2010-2022
Ewha Womans University Medical Center
2022
Gachon University
2019
Gwangju Institute of Science and Technology
2010-2019
Zero to Three
2018
Ministry of Food and Drug Safety
2017
University of Ulsan
2016
Sungkyunkwan University
2013-2015
This work demonstrates the way to achieve efficient and target specific delivery of a graphene quantum dot (GQD) using hyaluronic acid (HA) (GQD-HA) as targeting agent. HA has been anchored GQD that accepts fascinating adhesive properties catechol moiety, dopamine hydrochloride, conjugated HA, which was confirmed by X-ray photoelectron spectroscopy. Transmission electron microscopy revealed particle size ∼20 nm, fluorescence spectra significant intensity even after anchoring HA. The prepared...
Water soluble fluorescent carbon nanoparticles (FCP) obtained from a single natural source, mango fruit, were developed as unique materials for non-toxic bio-imaging with different colors and particle sizes. The prepared FCPs showed blue (FCP-B), green (FCP-G) yellow (FCP-Y) fluorescence, derived by the controlled carbonization method. demonstrated hydrodynamic diameters of 5–15 nm, holding great promise clinical applications. biocompatible potential in biological fields through results...
To enhance the ability of indirubin derivatives to inhibit CDK2/cyclin E, a target anticancer agents, we designed and synthesized new series indirubin-3′-oxime with combined substitutions at 5 5′ positions. A molecular docking study predicted binding OH or halogen position ATP site CDK2, revealing critical interactions that may explain improved CDK2 inhibitory activity these derivatives. Among derivatives, 5-nitro-5′-hydroxy analogue 3a 5-nitro-5′-fluoro 5a displayed potent against IC50...
Microglia activation plays a pivotal role in neurodegenerative diseases, and thus controlling microglial has been suggested as promising therapeutic strategy for diseases. In the present study, we showed that ginsenoside Rh1 inhibited inducible nitric oxide synthase, cyclooxygenase-2, pro-inflammatory cytokine expression lipopolysaccharide (LPS)-stimulated microglia, while increased anti-inflammatory IL-10 hemeoxygenase-1 (HO-1) expression. Suppression of by was also observed mouse brain...
This present article demonstrates the strategy to prepare photoresponsive reduced graphene oxide with mussel inspired adhesive material dopamine (DN) and photochromic dye spiropyran (SP) conjugated backbone of targeting ligand hyaluronic acid (HA; HA-SP). Graphene (GO) was by prepared HA-SP accepting advantages catechol chemistry under mildly alkaline condition enabling achieve functionalized (rGO/HA-SP) as fluorescent nanoparticles. Due containing HA, rGO/HA-SP can bind CD44 cell receptors....
We report a stimuli-responsive fluorescent nanomaterial, based on graphene oxide coupled with polymer conjugated photochromic spiropyran (SP) dye and hydrophobic boron dipyrromethane (BODIPY) dye, for application in triggered target multicolor bioimaging. Graphene (GO) was reduced by catechol-conjugated polymers under mildly alkaline conditions, which enabled to formation of functionalized nanoparticles that can be induced irradiation UV light changing the pH from acidic neutral....
This research introduces a method to directly detect serotonin in single platelet through single-entity electrochemistry. Platelets isolated from human blood were analyzed by cyclic voltammetry and current–time measurements. When collides with an ultramicroelectrode, inside the is oxidized at electrode surface, anodic current peak consequently observed during measurement. The concentration of can be determined integrating this current. In addition, used determine concentration. Analysis...
The objective of this study was to evaluate whether preoperative administration tamsulosin would decrease the frequency postoperative urinary retention (POUR) after mid-urethral sling (MUS) placement METHODS: This a prospective randomized, double-blinded, placebo-controlled trial patients with SUI who underwent elective MUS at single institution. Patients scheduled undergo consented, were enrolled, and randomized receive either tablet 0.4 mg or placebo in holding area on day their surgery....
Neovascular eye diseases are a major cause of blindness. Excessive angiogenesis is feature several conditions, including wet age-related macular degeneration, proliferative diabetic retinopathy, and retinopathy prematurity. Development novel antiangiogenic small molecules for the treatment neovascular disease essential to provide new therapeutic leads these diseases. We have previously reported potential anti-angiogenic homoisoflavanone derivatives with efficacy in retinal choroidal...
Herein, a study on new lower critical solution temperature (LCST) polymer in an organic solvent by electrochemical technique has been reported. The phase-transition behavior of poly(arylene ether sulfone) (PAES) was examined 1,2-dimethoxyethane (DME). At above the LCST point, molecules aggregated to create droplets. These droplets subsequently collided with ultramicroelectrode (UME), resulting form staircase current decrease. experimental collision frequency and signal were analyzed relation...
Abstract We studied the electrochemical detection of single nanosized water emulsion droplets in organic solution using collision technique on an ultramicroelectrode (UME). In this experiment, system for does not require any kind redox species solvent. Only molecules were considered. When collided with UME surface, anodic current spikes observed chronoamperometry, resulting from electrolysis droplets. From frequency and integrated spike, concentrations size distributions solvent can be determined.
Abstract Mesoporous polymer microspheres with gold (Au) nanoparticles inside their pores were prepared considering surface functionality and porosity. The Au/polymer composite characterized by transmission electron microscope (TEM), X‐ray diffraction (XRD), Brunauer–Emmett–Teller (BET) techniques. results showed that the adsorption of Au could be increased imparting pore structure surface‐functional groups into supporting (in this study, poly (ethylene glycol dimethacrylate‐ co...
This study introduces the electrochemical detection of a single microcystis on an Au ultramicroelectrode based single‐entity electrochemistry. The collisions occur when is adsorbed electrode surface. hinders oxidation electroactive redox species in solution, thus making current decrease like staircase. In this experiment, caused by collision which requires appropriate concentration and initial potential, providing information migration effect zeta‐potential, frequency. Comparison simulation...
Oxide scales often formed on the surface of stainless steel, and it is high interest to descale oxide effectively environment-friendly during steel smelting engineering processing. It generally done by treating layer under strong harsh mixed acid (HNO3 + HF) conditions or in a molten salt (NaOH NaNO3) environment at temperatures, while generation very harmful environmentally hazardous gases, such as NO x , inevitable. A novel, simple, fast, electrochemical method ambient temperature proposed...
Fms‑like tyrosine kinase 3 (FLT3) is a valuable pharmacological target in the treatment of acute myeloid leukemia (AML). LDD‑1075 and LDD‑1076 are indirubin derivatives, ester form LDD‑1076. exhibited potent vitro FLT3 activity inhibition with an IC50 7.89 nM, whereas, demonstrated relatively weak against (IC50 3.19 µM). In contrast results assay, did not affect growth MV4‑11 cell line, which harbors constitutively activated mutation. Notably, strong cytotoxic effect cells. When was...
An autonomous emergency braking (AEB) system based on Vehicle to (V2V) communication considering road friction at slopes was proposed in this study.Conventional AEB systems have limited performance of effective according conditions because they mostly consider only particular straight roads.To solve limitation, a new control logic calculate the timing by condition slopes.The TTC (time collision) method, which is collision risk, introduced information host vehicle and nearby vehicle.To verify...