- Radiation Dose and Imaging
- Advanced X-ray and CT Imaging
- Medical Imaging Techniques and Applications
- Advanced Radiotherapy Techniques
- Radiomics and Machine Learning in Medical Imaging
- Digital Radiography and Breast Imaging
- Neuroendocrine Tumor Research Advances
- Dental Radiography and Imaging
- Radiology practices and education
- Lung Cancer Research Studies
- Advanced MRI Techniques and Applications
- 3D Surveying and Cultural Heritage
- Neuroblastoma Research and Treatments
- MRI in cancer diagnosis
- Advanced Neuroimaging Techniques and Applications
- Image and Object Detection Techniques
- Advanced Vision and Imaging
- NMR spectroscopy and applications
- Dental Implant Techniques and Outcomes
- Radiation Therapy and Dosimetry
- Electrical and Bioimpedance Tomography
- Photoacoustic and Ultrasonic Imaging
- COVID-19 diagnosis using AI
- Cardiac Imaging and Diagnostics
- Radiation Detection and Scintillator Technologies
Azienda Ospedaliera Citta' della Salute e della Scienza di Torino
2016-2025
University of Turin
2006-2017
Azienda Ospedaliero Universitaria San Giovanni Battista
2004-2012
(1.1) to evaluate the association between baseline 18F-FDG PET/CT semi-quantitative parameters of primary lesion with progression free survival (PFS), overall (OS) and response immunotherapy, in advanced non-small cell lung carcinoma (NSCLC) patients eligible for immunotherapy; (1.2) application radiomics analysis identify features predictive (1.3) if tumor burden assessed by (N M factors) is associated PFS OS.we retrospectively analyzed clinical records NCSLC (stage IIIb/c or stage IV)...
Background There is lack of guidance on specific CT protocols for imaging patients with coronavirus disease 2019 (COVID-19) pneumonia. Purpose To assess international variations in utilization, protocols, and radiation doses COVID-19 Materials Methods In this retrospective data collection study, the International Atomic Energy Agency coordinated a survey between May July 2020 regarding from 62 health care sites 34 countries across five continents examinations performed The questionnaire...
Abstract Objective To identify the impact of segmentation methods and intensity discretization on radiomic features (RFs) extraction from 68 Ga-DOTA-TOC PET images in patients with neuroendocrine tumors. Methods Forty-nine were retrospectively analyzed. Tumor contouring was performed manually by four different operators a semi-automatic edge-based (SAEB) algorithm. Three SUV max fixed thresholds (20, 30, 40%) applied. Fifty-one RFs extracted applying two rescale factors for gray-level...
Gafchromic ® XR‐QA films were developed for patient dosimetry in diagnostic radiology. A possible application of these is the measurement doses computed tomography. In this study a method to evaluate CTDI using film and flatbed scanner was tested. Film samples cut dimensions order have an integration area similar that pencil ionization chamber, with possibility changing length. Prior exposing tomography beam, angular dependence dose response investigated by strips static x‐ray beam at...
There is a growing interest in Gafchromic® films for patient dosimetry radiotherapy and radiology. A new model (XR-QA) with high sensitivity to low dose was tested this study. The response of the film different x-ray beam energies (range 28–145 kVp various filtrations, range 0–100 mGy) visible light investigated, together after exposure darkening properties. Exposed were digitized commercially available, optical flatbed scanner. single functional form versus net pixel value variation has...
Our objective was to evaluate the prognostic value of somatostatin receptor tumor burden on 68Ga-DOTATOC PET/CT in patients with well-differentiated (WD) neuroendocrine tumors (NETs). Methods: We retrospectively analyzed scans 84 histologically confirmed WD NETs (51 grade 1, 30 2, and 3 3). For each scan, all 68Ga-DOTATOC-avid lesions were independently segmented by 2 operators using a customized threshold based healthy liver SUVmax (LIFEx, version 5.1). Somatostatin receptor-expressing...
Computed tomography scans are widely used in everyday medical practice due to speed, image reliability, and detectability of a wide range pathologies. Each scan exposes the patient radiation dose, performing fast estimation effective dose (E) is an important step for radiological safety. The aim this work estimate E from CT acquisition parameters absence dose-tracking software exploiting machine learning. In total, 69,037 acquisitions were collected with (DTS) available at our institution....
The aim of this study was to evaluate the impact on dose reduction and image quality new iterative reconstruction technique: adaptive statistical (ASIR-V).Fifty consecutive oncologic patients acted as case controls undergoing during their follow-up a computed tomography scan both with ASIR ASIR-V. Each analyzed in double-blinded fashion by 2 radiologists. Both quantitative qualitative analyses were conducted.Computed scanner radiation output 38% (29%-45%) lower (P < 0.0001) for ASIR-V...
Aim: This work aims to evaluate whether the radiomic features extracted by 68Ga-DOTATOC-PET/CT of two patients are associated with response peptide receptor radionuclide therapy (PRRT) in affected neuroendocrine tumor (NET). Methods: is a pilot report NET who experienced discordant PRRT (responder vs. non-responder) according RECIST1.1. The presented liver metastasis from rectum and pancreas G3-NET, respectively. Whole-body total-lesion somatostatin receptor-expression (TLSREwb-50)...
Aim: To evaluate if conventional Positron emission tomography (PET) parameters and radiomic features (RFs) extracted by 18F-FDG-PET/CT can differentiate among different histological subtypes of lung neuroendocrine neoplasms (Lu-NENs). Methods: Forty-four naïve-treatment patients on whom was performed for histologically confirmed Lu-NEN (n = 46) were retrospectively included. Manual segmentation two operators allowing extraction four PET (SUVmax, SUVmean, metabolic tumor volume (MTV), total...
The evaluation of radiation burden in vivo is crucial modern radiology as stated also the European Directive 2013/59/Euratom-Basic Safety Standard. Although dose monitoring can impact justification and optimization radiological procedure, well effective patient communication, standardization software far to be achieved. Toward this goal, Italian Association Medical Physics (AIFM) published a report describing state art standard guidelines system quality assurance. This article reports AIFM...
Quality controls for testing the performance of computed radiography (CR) systems have been recommended by manufacturers and medical physicists' organizations. The purpose this work was to develop a set image processing tools quantitative assessment quality control parameters. Automatic analysis consisted in detecting phantom details, defining regions interest acquiring measurements. tested characteristics included dark noise, uniformity, exposure calibration, linearity, low-contrast spatial...
Conventional radiology is performed by means of digital detectors, with various types technology and different performance in terms efficiency image quality. Following the arrival a new detector department, all staff involved should adapt procedure parameters to properties detector, order achieve an optimal result correct diagnostic information minimum radiation risks for patient. The aim this study was develop validate software capable simulating X-ray imaging system, using graphics...
The aim of this study was to evaluate various approaches for assessing patient organ doses resulting from radiotherapy cone-beam CT (CBCT), by the use thermoluminescent dosimeter (TLD) measurements in anthropomorphic phantoms, a Monte Carlo based dose calculation software, and different indicators as presently defined.Dose evaluations were performed on CBCT Elekta XVI (Elekta, Crawley, UK) protocols anatomical regions. first part focuses using pcxmc software (pcxmc 2.0, STUK, Helsinki,...