A5023720185- Bipolar Disorder and Treatment
- Tryptophan and brain disorders
- Functional Brain Connectivity Studies
- Mental Health Research Topics
- Treatment of Major Depression
- Electroconvulsive Therapy Studies
- Psychosomatic Disorders and Their Treatments
- COVID-19 and Mental Health
- Attention Deficit Hyperactivity Disorder
- Advanced Neuroimaging Techniques and Applications
- Suicide and Self-Harm Studies
- Child and Adolescent Psychosocial and Emotional Development
- Schizophrenia research and treatment
- Adolescent and Pediatric Healthcare
- Maternal Mental Health During Pregnancy and Postpartum
- Digital Mental Health Interventions
- Long-Term Effects of COVID-19
- Neural dynamics and brain function
- Diet and metabolism studies
- Dementia and Cognitive Impairment Research
- Genetics and Neurodevelopmental Disorders
- Sleep and Wakefulness Research
- Eating Disorders and Behaviors
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Sleep and related disorders
Guangzhou Medical University
2016-2025
The First People's Hospital of Shunde
2025
Chinese University of Hong Kong
2017-2024
Jinan University
2018-2024
University of Toronto
2020-2024
CTS Corporation (Czechia)
2024
V.F. Corporation (United States)
2024
Nanjing Brain Hospital
2024
Nanjing Medical University
2024
Bridge Pharma (United States)
2024
Depression is a recurrent and devastating mental disease that highly prevalent worldwide. Prolonged exposure to stressful events or environment detrimental health. In recent years, an inflammatory hypothesis has been implicated in the pathogenesis of stress-induced depression. However, less attention given initial phases, when series stress reactions immune responses are initiated. Peripheral CD4+ T cells have reported as major contributors occurrence disorders. Chronic exposure-evoked...
Rumination is a central feature of major depressive disorder (MDD). Knowledge the neural structures that underpin rumination offers significant insight into pathophysiology and may help to develop potential intervention strategies for MDD, mental illness has become leading cause disability worldwide.Using resting-state fMRI graph theory, this study adopted connectome approach examine functional topological organization network associated with in MDD. Data from 96 participants were analyzed,...
Abstract Aberrant structural (diffusion tensor imaging [DTI]) and resting‐state functional magnetic resonance imagining connectivity are core features of bipolar disorder. However, few studies have explored the integrity agreement between (SC–FC) in We examine SC coupling index whether could potentially provide additional clinical predictive value for disorder spectrum disorders besides intramodality network measures. By examining (DTI) properties, as well their index, among 57 euthymic...
To determine the effectiveness of intravenous (IV) ketamine on anxiety, irritability, agitation, and suicidality, in adults with treatment-resistant major depressive disorder (MDD) or bipolar (BD).Adults (N = 201) MDD BD received repeat-dose IV treatment at a community-based clinic. Mixed features were measured using symptoms agitation (AIA), as by Generalized Anxiety Disorder-7 (GAD-7) scale. The Quick Inventory for Depressive Symptomatology Self-Report-16 (QIDS-SR16 ) was used to measure...
Objectives Rigorous clinical trials suggest ketamine is safe and well-tolerated in patients with treatment-resistant depression (TRD). There a paucity of data on the safety tolerability community-based clinics treating TRD.Methods Retrospective was analyzed from 203 TRD who received repeat-dose IV ketamine. Safety operationalized as hemodynamic changes. Tolerability evaluated through reporting adverse events dissociation symptom severity, measured by Clinician-Administered Dissociative...
This study aimed to explore differences between psychological resilience and problem-solving ability in grade one junior middle school adolescents with without suicidal ideation, focusing on the relationship these factors ideation.Ninety-nine (aged 10 14) were divided into Suicidal Ideation (SI, n = 49) Non-Suicidal (NSI, 50) grouped by Self-rating Idea of Suicide Scale (SIOSS). The Psychological Resilience (PRS) Tower Hanoi task (TOH) applied assess ability, respectively.The SI group scored...
Sleep benefits the restoration of energy metabolism and thereby supports neuronal plasticity cognitive behaviors. Sirt6 is a NAD+-dependent protein deacetylase that has been recognized as an essential regulator because it modulates various transcriptional regulators metabolic enzymes. The aim this study was to investigate influence on cerebral function after chronic sleep deprivation (CSD). We assigned C57BL/6J mice control or two CSD groups subjected them AAV2/9-CMV-EGFP...