A5102880187- Hepatitis B Virus Studies
- Hepatitis C virus research
- Hepatitis Viruses Studies and Epidemiology
- Infectious Diseases and Tuberculosis
- Tuberculosis Research and Epidemiology
- Occupational Health and Safety Research
- Workplace Health and Well-being
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Safe Handling of Antineoplastic Drugs
- Amyotrophic Lateral Sclerosis Research
- Occupational and environmental lung diseases
- Vaccine Coverage and Hesitancy
- Radiopharmaceutical Chemistry and Applications
- Patient Safety and Medication Errors
- Bone health and treatments
- Nanoparticles: synthesis and applications
- Musculoskeletal pain and rehabilitation
- Ergonomics and Musculoskeletal Disorders
- Pesticide Exposure and Toxicity
- Insect and Pesticide Research
- Air Quality and Health Impacts
- Chemotherapy-induced organ toxicity mitigation
- Pesticide and Herbicide Environmental Studies
- COVID-19 and Mental Health
- Graphene and Nanomaterials Applications
University of Campania "Luigi Vanvitelli"
2014-2023
University of Naples Federico II
2011-2016
Institute of Occupational Medicine
2015
Nofer Institute of Occupational Medicine
2015
Universal hepatitis B virus (HBV) vaccination of newborn babies was introduced in Italy 1991 and extended to 12-years-old children for the first 12 years application so as cover a dozen Italian population aged 0-24 years. The aim this study identify factors associated with long-term immunogenicity against HBV 17 after primary students attending medical schools Naples, Italy.1,704 school medicine, healthcare professions, or postgraduate Second University Italy, from September 2012 December...
The development of a vaccine against hepatitis B virus (HBV) has been major achievement in terms prevention HBV infection. For the present study, we analysed long-term immunogenicity and effectiveness vaccination among healthcare students with different working seniorities.A cross-sectional study undergraduate postgraduate attending Medical School Second University Naples was conducted between September 2012 December 2014. serum markers were determined multivariate logistic regression...
Fluoropyrimidines are key agents for the treatment of gastrointestinal tract adenocarcinomas. The possible cardiotoxic effects in patients and occupationally exposed workers multifactorial remain a puzzle to solve investigators. In present study, we study what cell death pathways doses can determine direct 5-fluorouracil (5-FU) doxorubicin (DOXO) on rat cardiocytes (H9c2) human colon adenocarcinoma (HT-29) line, already reported be sensitive 5-FU. We have found that 5-FU induced 50% growth...
Pleural malignant mesothelioma (MPM) is a detrimental neoplasm affecting pleural sheets and determining high rate of mortality. In this study, we have enrolled 14 consecutive patients (13 males 1 female) with MPM (mean age: 70.3 ± 4.6 years). We collected serum for the determination miRNA profiling using low-density microarray real time PCR system in comparing it that one 10 control counterparts affected by not-cancer-related effusions. 5 miRNAs were up-regulated (miR101, miR25, miR26b,...
A cross-sectional study was carried out on 641 medical students, 359 students attending a degree course in the healthcare professions, and 500 resident physicians, all undergoing health surveillance at ambulatory of Division Occupational Medicine, Second University Naples, Italy. 76.1% participants drank alcohol, with 85.5% 77.4% 63% healthcare-professions reporting regular alcohol use. In whole sample, mean Audit-C score 1.6 for men 1.1 women; only 5.5% 7.1% women had hazardous consumption...
Purpose. The SARS-CoV-2 pandemic has affected all aspects of everyday life worldwide, including the entire working sector. This study aims to evaluate response capacity some Italian companies emergency about workers' health and safety. Methods. Data were cross-sectional, collected by a specially drafted 19-item checklist sent 60 enterprises located in province L'Aquila, Abruzzo, Italy. Results. Forty-one (68%) responded filling checklist; more than 50% have fewer 50 employees each most...
To study aluminum (Al), manganese (Mn), and lead (Pb) influence on amyotrophic lateral sclerosis (ALS) development.A total of 34 patients (10% the regional ALS population) 25 controls an Italian region were enrolled. Metal concentrations determined by atomic absorption spectroscopy.Serum Al in similar lower than those provided Society Reference Values. No differences observed serum Mn concentrations, while, as expected, blood Pb levels significantly higher with controls.Results confirmed...
In recent years, scientific literature has been giving more and importance to the study of occupational/environmental exposure risk agents related onset Amyotrophic Lateral Sclerosis (ALS), a neurodegenerative disease characterized by progressive muscular paralysis reflecting degeneration motor neurons in primary cortex. Aim this work is verify state art about eventual role occupationall environmental agents. Selected articles, on basis keywords, year publication topics, are occupational...
Coronary heart disease is frequent in the working-age population. Traditional outcomes, such as mortality and hospital readmission, are useful for evaluating prognosis. Fit-for-work an emerging outcome with clinical well socioeconomic significance. We describe possible benefit of a cardiac rehabilitation (CR) program return to work (RTW) after acute coronary syndrome (ACS).We evaluated 204 patients recent ACS. They were divided into 4 groups on basis their occupational load: very light (VL),...
The risk of tuberculosis (TB) in healthcare personnel (HCP) is related to its incidence the general population. Healthcare students involved clinical training could be exposed occupational risks similar those that HCP face. prevalence latent infection (LTBI) among undergraduate with different working seniority Italy was analysed.A cross-sectional study under a screening programme for LTBI and postgraduate attending Medical School at Second University Naples conducted between January 2012...
5-Fluorouracil (5-FU), often used in combination with levofolene (LF), can induce, as an important side effect, the hand-foot syndrome (HFS) due to toxicity on keratinocytes. This also damage workers involved its handling. In present study, we investigated mechanisms of induced by 5-FU alone or together LF human keratinocytes culture. We found that two drugs, expected, had potentiating activity keratinocyte growth inhibition and this effect was mediated induction apoptosis. our experimental...