- Transcranial Magnetic Stimulation Studies
- Functional Brain Connectivity Studies
- Neural and Behavioral Psychology Studies
- Pain Management and Treatment
- Migraine and Headache Studies
- Electroconvulsive Therapy Studies
- Neural dynamics and brain function
- EEG and Brain-Computer Interfaces
- Obsessive-Compulsive Spectrum Disorders
- Muscle activation and electromyography studies
- Control and Dynamics of Mobile Robots
- Fusion and Plasma Physics Studies
- Treatment of Major Depression
- Optical Imaging and Spectroscopy Techniques
- Family and Disability Support Research
- Sleep and related disorders
- Genetics and Neurodevelopmental Disorders
- Hearing Loss and Rehabilitation
- Energy Harvesting in Wireless Networks
- Experimental and Theoretical Physics Studies
- Mind wandering and attention
- Microgrid Control and Optimization
- Robotic Locomotion and Control
- Hearing, Cochlea, Tinnitus, Genetics
- Vestibular and auditory disorders
Princess Margaret Hospital for Children
2025
The University of Western Australia
2025
NOAA National Centers for Environmental Information
2023-2024
Cooperative Institute for Research in Environmental Sciences
2023-2024
University of Colorado Boulder
2023-2024
Neurobehavioral Systems
2019-2023
University of California, Los Angeles
2019-2022
UCLA Health
2019
University of British Columbia
2014
Abstract Repetitive transcranial magnetic stimulation (rTMS) treatment of major depressive disorder (MDD) is associated with changes in brain functional connectivity (FC). These may be related to the mechanism action rTMS and explain variability clinical outcome. We examined electroencephalographic FC during first 109 subjects treated 10 Hz left dorsolateral prefrontal cortex. All subsequently received 30 treatments response was defined as ≥40% improvement inventory symptomatology-30 SR...
The aim of the current study was to attempt replicate finding that individual alpha frequency (IAF) as well absolute difference between IAF and 10 Hz stimulation (IAF-prox) is related treatment outcome. Correlations were performed investigate relationship IAF-prox percentage symptom improvement in a sample 153 patients with major depressive disorder treated (N = 59) left dorsolateral prefrontal cortex (DLPFC) or 1 94) right DLPFC repetitive Transcranial Magnetic Stimulation (rTMS). There...
Clinical outcomes of repetitive transcranial magnetic stimulation (rTMS) for treatment treatment-resistant depression (TRD) vary widely and there is no mood rating scale that standard assessing rTMS outcome. It remains unclear whether TMS as efficacious in older adults with late-life (LLD) compared to younger major depressive disorder (MDD). This study examined the effect age on TRD. Self-report observer ratings were measured weekly 687 subjects ages 16–100 years undergoing using Inventory...
Major depressive disorder (MDD) and chronic pain are highly comorbid, symptoms associated with a poorer response to antidepressant medication treatment. It is unclear whether comorbid also treatment repetitive transcranial magnetic stimulation (rTMS).162 MDD subjects received 30 sessions of 10 Hz rTMS administered the left dorsolateral prefrontal cortex (DLPFC) depression measured before after For subset 96 patients, resting-state electroencephalogram (EEG) was recorded at baseline. Clinical...
Background Symptoms of major depressive disorder (MDD) are reported to change early in treatment with repetitive transcranial magnetic stimulation (rTMS). We evaluated changes sleep, anxiety, and mood as predictors nonresponse rTMS treatment. Methods Three hundred twenty-nine subjects nonpsychotic MDD completed a 6-week course Subjects were stratified by the severity their baseline depression, had overall symptoms recorded every week lack improvement after 1 2 weeks potential eventual...
Abstract Rumination is a maladaptive style of regulating thoughts and emotions. It common symptom Major Depressive Disorder (MDD), more severe rumination associated with poorer medication psychotherapy treatment outcomes, particularly among women. unclear to what extent may influence the outcomes of, or be responsive to, repetitive Transcranial Magnetic Stimulation (rTMS) MDD. We retrospectively examined data collected during rTMS 155 patients (age 42.52 ± 14.22, 79 female) moderately...
Intermittent theta-burst stimulation priming (iTBS-P) can improve clinical outcome of patients with Major Depressive Disorder (MDD) who do not show early benefit from 10 Hz left dorsolateral prefrontal cortex (DLPFC), also known as high-frequency left-sided (HFL) stimulation. The intensity and pulse number for iTBS-P needed to induce have been systematically examined.To study the effect on efficacy iTBS-P.We conducted a retrospective review 71 participants received at least five sessions HFL...
Autistic adolescents are vulnerable to sleep difficulties, with up 80 % experiencing problems, most commonly insomnia. Little is known about how autistic involved in their own treatment, and depth of knowledge difficulties. The aims this study were investigate adolescent parent perspectives managing insomnia, what factors influence the development these on insomnia treatment. Semi-structured interviews conducted 11 (45 female, mean age 11.6 years) 16 parents an (94 45.1 years). A qualitative...
There is evidence that the learning benefits of contextual interference (CI) are moderated by experience, yet we do not know if these experiences related to specific practice with random schedules. In two experiments, CI schedule was manipulated on Day 1. We evaluated its impact 3 new tasks 2; in same or different (Experiment 1) when participants chose their 2). Typical effects were observed for both sets tasks, although 2, there no longer any costs from practice. Previous affected how...
Background Repetitive transcranial magnetic stimulation (rTMS) is an effective treatment for major depressive disorder (MDD). Psychostimulant medication use may be associated with improved rTMS outcomes, but a detailed understanding of these relationships lacking. Methods We compared MDD subjects taking psychostimulants (n = 37) those not one medications 53) during course 30 treatments. Changes in the 30-item Inventory Depressive Symptomatology Self Report (IDS-SR30) subscale scores were...
BackgroundRepetitive Transcranial Magnetic Stimulation (rTMS) is an effective treatment for Major Depressive Disorder (MDD), but therapeutic benefit highly variable. Clinical improvement related to changes in brain circuits, which have preferred resonant frequencies (RFs) and vary across individuals.ObjectiveWe developed a novel rTMS-electroencephalography (rTMS-EEG) interrogation paradigm identify RFs using the association of power/connectivity measures with symptom severity...
Pre-treatment biomarkers for outcome of repetitive Transcranial Magnetic Stimulation (rTMS) treatment Major Depressive Disorder (MDD) have proven elusive. One promising family involves the autonomic nervous system (ANS), which is dysregulated in individuals with MDD. We examined relationship between pre-treatment pupillary light reflex (PLR) and rTMS 51 MDD patients. Outcome was measured as percent change 30-item Inventory Symptomatology Self Rated (IDS-SR) score from baseline to 30....
Background Tinnitus distress is related to both the loudness and intrusiveness of tinnitus percept. Treatment approaches targeting attentional/limbic auditory systems may better alleviate than system alone. Materials Methods Ten subjects with chronic received sequential rTMS treatment involving: 1) excitatory stimulation administered left dorsolateral prefrontal cortex (DLPFC) or inhibitory right DLPFC, followed by 2) primary (Heschel's gyrus HG). A systematic literature review was performed...