Lihua Dai

ORCID: 0009-0004-1855-5212
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About
Contact & Profiles
Research Areas
  • Spine and Intervertebral Disc Pathology
  • Medical Imaging and Analysis
  • Spinal Fractures and Fixation Techniques
  • Bone fractures and treatments
  • Acute Ischemic Stroke Management
  • Musculoskeletal pain and rehabilitation
  • Anesthesia and Pain Management
  • Gastric Cancer Management and Outcomes
  • Spinal Cord Injury Research
  • Orthopaedic implants and arthroplasty
  • Neuropeptides and Animal Physiology
  • MicroRNA in disease regulation
  • Soil Management and Crop Yield
  • Soil Carbon and Nitrogen Dynamics
  • Airway Management and Intubation Techniques
  • Bone and Joint Diseases
  • interferon and immune responses
  • Immune Cell Function and Interaction
  • Pain Mechanisms and Treatments
  • Pelvic and Acetabular Injuries
  • Lung Cancer Diagnosis and Treatment
  • Muscle and Compartmental Disorders
  • Hypothalamic control of reproductive hormones
  • Cancer-related cognitive impairment studies
  • Extracellular vesicles in disease

Shanghai Jiao Tong University
2006-2025

Shanghai First People's Hospital
2023-2025

China National Petroleum Corporation (China)
2025

Central Hospital of Zibo
2025

Huadong Hospital
2024

University of Shanghai for Science and Technology
2023-2024

Guizhou Academy of Sciences
2024

Xiangtan University
2023

Shanghai Pulmonary Hospital
2020-2021

Tongji University
2020-2021

To further our understanding of the pathobiology esophageal squamous cell carcinoma (ESCC), we previously performed microRNA profiling that revealed downregulation miR-200b in ESCC. Using quantitative real-time PCR applied to 88 patient samples, confirmed ESCC tumors expressed significantly lower levels compared with respective adjacent benign tissues ( P = 0.003). Importantly, correlated shortened survival 0.025), lymph node metastasis 0.002) and advanced clinical stage 0.020) patients....

10.1093/carcin/bgt320 article EN Carcinogenesis 2013-09-24

Aim: This prospective study aimed to evaluate the relationship between ratio of C-reactive protein-to-prealbumin (CRP/PAB) and clinical outcomes in medical intensive care unit patients. Materials & methods: All 240 consecutive adult patients were enrolled this with demographic features collected. Results: Compared belonging CRP/PAB ≤0.24 group, hospital mortality total length stay (TLSH) significantly increased >0.24 group. Acute Physiology Chronic Health Evaluation II score independently...

10.2217/bmm-2016-0266 article EN Biomarkers in Medicine 2017-03-14

Isoquercetin has exhibited a wide range of therapeutic properties, including antioxidant, anti-inflammatory and anti-allergic activities. The aim the present study was to investigate effect isoquercetin on rats with 2 h middle cerebral artery occlusion (MCAO) evaluate neuroprotective primary culture rat hippocampal neuronal cells subjected oxygen-glucose deprivation followed by reoxygenation (OGD/R). In vivo, treated lower degree neurological dysfunction smaller infarct volume than...

10.3892/etm.2017.4093 article EN Experimental and Therapeutic Medicine 2017-01-31

Abstract Faults play a crucial role in the exploration and development of oil gas resources. In recent years, deep learning algorithms for fault interpretation have shown signs progress are still rapid stage. Since most research at this stage uses 3D synthetic data, ignoring complex geological structure field data. This paper focus on training data issue, using true sticks as labels. An interactive generation tool is utilized to automatically establish pairs seismic labels, forming 2D set...

10.2523/iptc-24864-ea article EN International Petroleum Technology Conference 2025-02-17

ABSTRACT In this research, we conducted an in‐depth analysis of differentially expressed genes associated with mitochondrial depolarisation in non‐small cell lung cancer (NSCLC) using single‐cell sequencing. By combining our findings cuproptosis‐related genes, identified 10 significant risk genes: DCN, PTHLH, CRYAB, HMGCS1, DSG3, ZFP36L2, SCAND1, NUDT4, NDUFA4L2 and RPL36A, univariate Cox regression machine learning methods. These form the core prognosis prediction model, which demonstrated...

10.1111/jcmm.70438 article EN cc-by Journal of Cellular and Molecular Medicine 2025-02-01

Abstract The cardiovascular system is pivotal in the systemic distribution and toxicity of nanoparticles (NPs) upon their entry into circulation. Therefore, it crucial to extensively investigate adverse effects NPs. This review presents advancements understanding NPs potential effects, particularly humans. We first discussed uptake tissues cells, which result outcomes such as hemolysis, blood coagulation dysfunction, vascular endothelial damage, cardiac pathological damage function...

10.1515/ntrev-2025-0161 article EN cc-by Nanotechnology Reviews 2025-01-01

Nasopharyngeal carcinoma (NPC) is prevalent in Southern China and Southeast Asia, autoantibody signatures may improve early detection of NPC. In this study, serum levels autoantibodies against a panel six tumor-associated antigens (p53, NY-ESO-1, MMP-7, Hsp70, Prx VI, Bmi-1) Epstein-Barr virus capsid antigen-IgA (VCA-IgA) were tested by enzyme-linked immunosorbent assay training set (220 NPC patients 150 controls) validated validation (90 68 controls). We used receiver-operating...

10.1158/1940-6207.capr-14-0397 article EN Cancer Prevention Research 2015-05-20

Abstract Telocytes (TCs) are a new type of interstitial cell identified in multiple tissues mammals, including the human lung, and mediate homocellular or heterocellular cell‐cell communication. Acute respiratory distress syndrome (ARDS) is characterized by acute hypoxemia failure combined with direct indirect lung injury, which induced pneumonia, sepsis, burns, etc. Pulmonary fibrosis progressive disease that occurs due to increased tissue response chronic injury epithelium gets more...

10.1002/ctd2.277 article EN cc-by Clinical and Translational Discovery 2024-03-11
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