A5049304491- Pediatric Urology and Nephrology Studies
- Emergency and Acute Care Studies
- Urinary Tract Infections Management
- Neonatal Health and Biochemistry
- Neonatal and Maternal Infections
- Pneumonia and Respiratory Infections
- Urological Disorders and Treatments
- Ultrasound in Clinical Applications
- Respiratory viral infections research
- Trauma and Emergency Care Studies
- Neonatal Respiratory Health Research
- Nosocomial Infections in ICU
- Bacterial Infections and Vaccines
- Cardiac, Anesthesia and Surgical Outcomes
- Appendicitis Diagnosis and Management
- Migration, Health and Trauma
- Child and Adolescent Health
- Sexual function and dysfunction studies
- Cardiovascular Effects of Exercise
- Hospital Admissions and Outcomes
- Antibiotic Use and Resistance
- Neonatal and fetal brain pathology
- Interpreting and Communication in Healthcare
- Abdominal Trauma and Injuries
- Injury Epidemiology and Prevention
The University of Texas at Austin
2024-2025
Dell Children's Medical Center of Central Texas
2024
University of Washington
2019-2022
Cincinnati Children's Hospital Medical Center
2018-2021
Seattle Children's Hospital
2019-2021
University of Cincinnati
2018-2021
Children's Hospital of Philadelphia
2015-2016
Washington University in St. Louis
2014
Children's Hospital of Pittsburgh
2011
To derive and internally validate a prediction model for the identification of febrile infants ≤60 days old at low probability invasive bacterial infection (IBI).We conducted case-control study who presented to emergency departments 11 hospitals between July 1, 2011 June 30, 2016. Infants with IBI, defined by growth pathogen in blood (bacteremia) and/or cerebrospinal fluid (bacterial meningitis), were matched hospital date visit 2 control patients without IBI. Ill-appearing those complex...
To determine the association between parenteral antibiotic duration and outcomes in infants ≤60 days old with bacteremic urinary tract infection (UTI).This multicenter retrospective cohort study included who had concomitant growth of a pathogen blood urine cultures at 11 children's hospitals 2011 2016. Short-course was defined as ≤7 days, long-course >7 days. Propensity scores, calculated using patient characteristics, were used to likelihood receiving antibiotics. We conducted inverse...
: media-1vid110.1542/5840460609001PEDS-VA_2018-1879Video Abstract OBJECTIVES: To evaluate the Rochester and modified Philadelphia criteria for risk stratification of febrile infants with invasive bacterial infection (IBI) who do not appear ill without routine cerebrospinal fluid (CSF) testing.We performed a case-control study ≤60 days old presenting to 1 9 emergency departments from 2011 2016. For each infant IBI (defined as blood [bacteremia] and/or CSF [bacterial meningitis] culture growth...
OBJECTIVES: We sought to determine the time pathogen detection in blood and cerebrospinal fluid (CSF) for infants ≤60 days old with bacteremia and/or bacterial meningitis explore whether differed non–ill-appearing ill-appearing infants. METHODS: included evaluated emergency departments of 10 children’s hospitals between July 1, 2011, June 30, 2016. The microbiology laboratories at each site were queried identify whom a was isolated from CSF. Medical records then reviewed confirm presence...
OBJECTIVES Children with certain congenital anomalies of the kidney and urinary tract neurogenic bladder (CAKUT/NGB) are at higher risk treatment failure for infections (UTIs) than children normal genitourinary anatomy, but literature describing outcomes is limited. The objectives this study were to describe rate in CAKUT/NGB compare duration antibiotics between those without failure. METHODS Multicenter retrospective cohort 0 17 years old who presented emergency department fever or...
Children with a language for care other than English (LOE) are at risk inequitable care. We examined the association of isolation precautions in hospitalized children LOE through frequency professional interpreter use and timing in-person consultation. Retrospective cohort study strict unit (SIU) between 2/2020 12/2021. Negative binomial regression was used to assess both differences interpretation rates SIU non-SIU, within 72-h/in-person consultation English-speaking encounters. identified...
OBJECTIVE In children with urinary tract anomalies, febrile infections (UTIs) are associated increased risks of sepsis, hospitalization, and kidney injury. However, the best treatment strategies unknown. We aimed to describe antibiotic practices outcomes for UTIs in anomalies evaluate whether variability UTI exists between hospitals. METHODS conducted a multicenter retrospective cohort study seen emergency departments (EDs) 6 free-standing US children’s hospitals from January 1, 2017,...
Objective We aimed to evaluate the association of height fever with invasive bacterial infection (IBI) among febrile infants <=60 days age. Methods In a secondary analysis multicentre case–control study non-ill-appearing age, we compared maximum temperature (at home or in emergency department) for and without IBI. then computed interval likelihood ratios (iLRs) diagnosis IBI at each half-degree Celsius interval. Results The median was higher (38.8°C; IQR 38.4–39.2) those (38.4°C;...
The yield of blood cultures in children hospitalized with community-acquired pneumonia (CAP) is low. Characteristics at increased risk bacteremia remain largely unknown.We conducted a secondary analysis retrospective cohort study aged 3 months to 18 years CAP 6 children's hospitals from 2007 2011. We excluded complex chronic conditions and without performed admission. Clinical, laboratory, microbiologic, radiologic data were assessed identify predictors bacteremia.Among 7509 CAP, 2568...
OBJECTIVES: To describe the characteristics and outcomes of afebrile infants ≤60 days old with invasive bacterial infection (IBI). METHODS: We conducted a secondary analysis cross-sectional study IBI presenting to emergency departments (EDs) 11 children’s hospitals from 2011 2016. classified as if there was absence temperature ≥38°C at home, referring clinic, or in ED. Bacteremia meningitis were defined pathogenic growth blood and/or cerebrospinal fluid culture. RESULTS: Of 440 IBI, 78 (18%)...
Abstract Background Radiologic imaging is routinely performed to aid in diagnosis for hospitalized children. Identifying and reducing variability practices can improve care while harms costs. Objectives To identify common inpatient pediatric conditions with high prevalence of variation imaging‐related costs across hospitals. Methods We conducted a cross‐sectional study children 0–18 years old admitted 50 children's hospitals the Pediatric Health Information Systems database between 2017...
OBJECTIVES: We aimed to describe the cerebrospinal fluid (CSF) profiles of infants ≤60 days old with bacterial meningitis and characteristics who did not have CSF abnormalities. METHODS: included culture-positive were evaluated in emergency departments 11 children’s hospitals between July 1, 2011, June 30, 2016. From medical records, we abstracted clinical laboratory data. For traumatic lumbar punctures (CSF red blood cell count ≥10 000 cells per mm3), used a count/white (WBC) correction...
OBJECTIVES This study aimed to describe variation in imaging practices and examine the association between early outcomes children hospitalized with cervical lymphadenitis. METHODS multicenter cross‐sectional included two months 18 years lymphadenitis 2013 2017. Children complex chronic conditions, transferred from another institution, prior hospitalizations for were excluded. To hospital‐level variation, we calculated proportion of at each hospital who received any study, (conducted on day...
In this secondary analysis of the Randomized Intervention for Children with Vesicoureteral Reflux cohort, we found that daily prophylaxis trimethoprim-sulfamethoxazole was not associated an increased or decreased risk skin and soft tissue infections, pharyngitis sinopulmonary infections in otherwise healthy children 2–71 months age.
To describe testing and treatment practices for Mycoplasma pneumoniae (Mp) among children hospitalized with community-acquired pneumonia (CAP).We conducted a retrospective cohort study using the Pediatric Health Information Systems database. We included 3 months to 18 years old CAP between 2012 2018 excluded who were transferred from another hospital those complex chronic conditions. examined proportion of patients receiving Mp macrolide therapy at level trends in prescription over time. At...
OBJECTIVES: We aimed to describe the clinical and laboratory characteristics of febrile infants ≤60 days old with positive urinalysis results invasive bacterial infections (IBI). METHODS: performed a planned secondary analysis retrospective cohort study IBI who presented 11 emergency departments from July 1, 2011, June 30, 2016. For this subanalysis, we included results. analyzed sensitivity high-risk past medical history (PMH) (prematurity, chronic condition, or recent antimicrobial...
BACKGROUND Febrile infants aged 0 to 60 days are often hospitalized for a 36‐to‐48 hour observation period rule out invasive bacterial infections (IBI). Evidence suggests that monitoring blood and cerebrospinal fluid (CSF) cultures 24 hours may be appropriate most infants. We aimed decrease the average culture time (COT) from 38 30 among old over 12 months. METHODS This quality improvement initiative occurred at large children's hospital, in conjunction with development of multidisciplinary...