ЭКСПЕРИМЕНТАЛЬНАЯ МОДЕЛЬ ДЛЯ ИЗУЧЕНИЯ МЕХАНИЗМА НЕЗАВИСИМОЙ ОТ ЛИМФОЦИТОВ ПОЛЯРИЗАЦИИ МАКРОФАГОВ В КИШЕЧНИКЕ МЫШЕЙ

• DOI: 10.31857/s102872210006651-1
• Publication Date: 2020-06-17
• Authors: Ekaterina A. Litv...; Kseniya M. Achasova

Acute inflammatory begins to activate of M1-macrophage by classical pathway. In the chronic form disease, body triggers an adaptive alternative pathway M2-macrophages. For example, number intestinal M2-macrophages increases in infl ammatory bowel disease (IBD) a form. We have got model mice that do not mature lymphocytes and these animals development IBD due absence mucosal barrier. obtained good reveals role macrophages IBD, can also be used understand effect pharmacological drugs cause polarization macrophages.