Clinical analysis of bilateral native pelvic and ureteral transitional cell carcinoma following renal transplantation

• DOI: 10.3760/cma.j.issn.0254-1785.2011.08.007
• Publication Date: 2011-08-20
• Authors: Wei Wang; Hang Yin; Xiaobei Li; Xiaoyong Yang; Liang Ren; Hang Liu; Peng Zhang; Xiao Hu; Yong Wang; Xiaodong Zhang
• Keywords: Upper urinary tract; Renal pelvis

Objective To investigate the clinical features of bilateral native pelvic and ureteral transitional cell carcinoma (TCC) in renal transplant patients. Methods A retrospective analysis was carried out on 16 patients with TCC after kidney transplantation.The mean time between transplantation diagnosis upper urinary 56. 2 ± 33. 0 months.Two were suffered from at same time. The interval tract operations remaining 14 cases 8. 6 6. 7 months. Hematuria hydronephrosis kidneys main symptoms targets checkup. Intravesical chemotherapy postoperatively given. Results All performed successfully. specimens obtained pathologically diagnosed as TCC. location involved pure pelvis (n = 4), ureter 9), combined 19). Pelvic pathological grades included grade 1 8 cases, 11 3 4 cases; Ureteral 10 12 cases.Patients followed up for 26. 25. One patient died lung metastasis. (One case lumbar soft tissue transfer given local excision. had no recurrence Conclusion Renal hematuria should be highly vigilant occurrence is invasive. Prophylactic contralateral nephroureterectomy recipients having bladder one side tract.

Key words: Kidney transplantation; tumor; Ureter Transitional