A comparative split-face study of intense pulsed light versus 595-nm pulsed dye laser in the treatment of post-acne erythema

• DOI: 10.3760/cma.j.issn.0412-4030.2017.03.006
• Publication Date: 2017-03-15
• Authors: Hong Su; Zhi Yang; Yaxin Tan; Hang Shi; Yuan Chen; Song Jiang; Yiqiong Zhang; Ying Xiong; Li He
• Keywords: Erythema; Intense pulsed light

Objective To evaluate and compare the clinical efficacy safety of intense pulsed light (IPL) versus 595-nm dye laser (PDL) for treatment post-acne erythema.

Methods A randomized split-face trial was conducted. A total 20 patients with erythema were enrolled, to receive IPL on one half face PDL other facial side once every 4 weeks 3 sessions. Digital photographs taken using VISIA, index recorded before each month after last treatment. The severity bilateral evaluated based a 4-point grading scale first Pain scores adverse reactions visual analogue (VAS) treatment, patient satisfaction survey conducted by questionnaire at follow-up.

Results The mean 472.25 ± 86.02 357.15 82.71 respectively, that 476.40 74.25 360.05 64.83 respectively. Repeated measures analysis variance (ANOVA) showed indices both treated sides significantly decreased over time (F= 197.666, P 0.05) . included erythema, burning sensation, tense blistering hyperpigmentation IPL-treated side, purpuric PDL-treated which all disappeared in few hours several days.

Conclusions Both are effective safe worthy promotion application. shows superiority efficacy, but elicits higher pain sensation compared PDL.

Key words: Acne vulgaris; Lasers, dye; Randomized controlled trial; Post-acne erythema; Intense