The changes of transcranial sonography in end-stage renal disease with restless legs syndrome

• DOI: 10.3760/cma.j.issn.1004-4477.2019.10.006
• Publication Date: 2019-10-25
• Authors: Caishan Wang; Jing Luo; Hui Li; Yujing Sheng; Ying Zhang; Zhoubing Zhan; Yingchun Zhang
• Keywords: Restless Legs Syndrome; Echogenicity

Objective To discuss the neuroimaging characteristics of transcranial ultrasound in end-stage renal disease (ESRD) with restless legs syndrome.

Methods Transcranial sonography (TCS) was performed ESRD syndrome (RLS+ group, n=41), without (RLS- n=57) and control group (n=47), who were enrolled Second Affiliated Hospital Soochow University from January 2017 to December 2018. The differences TCS substantia nigra (SN), brainstem raphe (BR) red nucleus(RN) among three groups analyzed.

Results The rate SN hypoechogenicity significantly higher RLS+ (36.6%, 15/41) than that RLS- (19.3%, 11/57) group(8.5%, 4/47) (χ2=10.6, P<0.05). abnormal BR echogenicity (34.1%, 14/41) (29.8%, 17/57) group(10.6%, 5/47) (χ2=7.7, RN hyperechogenicity (51.2%, 21/41) (21.1%, 12/57) (10.6%, (χ2=19.8, Between groups, when SN, all positive performance, accuracy diagnosing reached 70% (7/10).

Conclusions The changes on could provide valuable information for clinical diagnosis treatment syndrome.

Key words: Ultrasonography, Doppler, transcranial; Substantia nigra; Brainstem raphe; Red nucleus