Non-alcoholic fatty liver disease and liver transplantation

• DOI: 10.3760/cma.j.issn.1007-8118.2020.02.017
• Publication Date: 2020-02-28
• Authors: Pengcheng Zhang; Kefeng Dou; Zhao-Xu Yang; Ruohan Zhang; Hongtao Zhang; Peng Wei; Yanbing Cao; Weimin Li
• Keywords: Pathogenesis; Liver disease; Chronic liver disease

Non-alcoholic fatty liver disease (NAFLD) is characterized by increased fat depositions in the while patients do not have drinking history. NAFLD has a prevalence of 10%~40% global, 25%~26% Western populations. From 2004 to 2013, numbers new on waitlist who had NASH 170% America. The China 20%. With decrease HBV and HCV increase diabetes mellitus type 2 obesity, will become most common chronic over next 20 years. related end-stage indication transplantation. In this paper, epidemiological features, pathogenesis, prognosis transplantation are reviewed.

Key words: Liver transplantation; Metabolic syndrome; Fatty liver, non-alcoholic