Advances in antifungal prophylaxis after allogeneic hemotopoietic stem cell transplantation

• DOI: 10.3760/cma.j.issn.1673-419x.2015.01.009
• Publication Date: 2015-01-20
• Authors: Xiaoyu Zhang; Rongli Zhang
• Keywords: Hematopoietic stem cell

Fungal infections, especially invasive fungal disease(IFD) is one of the major causes which incresae mortality after allogeneic hematopoietic stem cell transplantation(allo-HSCT). Several researches have confirmed that optimal antifungal prophylaxis can reduce risks proven or probable infections in allo-HSCT patients. However, epidemiology characteristic pathogen, as well immunity reconstruction patients should be taken into account when making decisions on choice prophylactic agents. This article reviews literatures advances allo-HSCT.

Key words: Hematopoietic transplantaion; Mycoses; Antifungal agents