A5100419404- Antifungal resistance and susceptibility
- Tissue Engineering and Regenerative Medicine
- Fungal and yeast genetics research
- Animal Disease Management and Epidemiology
- Reconstructive Surgery and Microvascular Techniques
- Musculoskeletal pain and rehabilitation
- Plant-Microbe Interactions and Immunity
- Corrosion Behavior and Inhibition
- Viral gastroenteritis research and epidemiology
- Medical Imaging and Analysis
- Tryptophan and brain disorders
- Nail Diseases and Treatments
- Metal and Thin Film Mechanics
- Sperm and Testicular Function
- Metal Extraction and Bioleaching
- Semiconductor materials and devices
- Microbial Fuel Cells and Bioremediation
- Reproductive Biology and Fertility
- Mine drainage and remediation techniques
- Reproductive System and Pregnancy
- Inflammasome and immune disorders
- Viral Infections and Immunology Research
- Breast Cancer Treatment Studies
- Fungal Infections and Studies
- Spine and Intervertebral Disc Pathology
Hubei University
2025
Wuhan Institute of Bioengineering
2023
Donghua University
2021
Chinese Academy of Medical Sciences & Peking Union Medical College
2020
Dana-Farber/Harvard Cancer Center
2020
Zunyi Medical University
2019
Institute of Hematology & Blood Diseases Hospital
2015
Abstract Background Many adult women younger than 40 years old have premature ovarian failure (POF) and infertility. Previous studies confirmed that different tissue-derived stem cells could restore function folliculogenesis in chemotherapy-induced POF mice. The aim of this study was to explore the therapeutic efficacy underlying mechanisms human amniotic mesenchymal (hAMSCs) transplantation for hydrogen peroxide-induced damage. Methods Bilateral ovaries female mice were burned with 10%...
Outbreaks of hand, foot and mouth disease (HFMD) have occurred frequently in the Asian-Pacific region over last two decades, caused mainly by serotypes Enterovirus A species. High-quality monoclonal antibodies (mAbs) are needed to improve accuracy efficiency diagnosis enteroviruses associated HFMD. In this study, a mAb 1A11 was generated using full particles CV-A5 as an immunogen. indirect immunofluorescence Western blotting assays, bound viral proteins CV-A2, CV-A4, CV-A5, CV-A6, CV-A10,...
Biofilm plays an important role in fungal multidrug resistance (MDR). Our previous studies showed that BSC2 is involved to amphotericin B (AMB) through antioxidation Saccharomyces cerevisiae. In this study, the overexpression of and IRC23 induced strong MDR S. BSC2-overexpression affected cellular flocculation, cell surface hydrophobicity, biofilm formation invasive growth. However, it failed induce caspofungin (CAS) affect growth FLO mutant strains (FLO11Δ, FLO1Δ, FLO8Δ TUP1Δ). Furthermore,...
Fungal infections, especially invasive fungal disease(IFD) is one of the major causes which incresae mortality after allogeneic hematopoietic stem cell transplantation(allo-HSCT). Several researches have confirmed that optimal antifungal prophylaxis can reduce risks proven or probable infections in allo-HSCT patients. However, epidemiology characteristic pathogen, as well immunity reconstruction patients should be taken into account when making decisions on choice prophylactic agents. This...
Despite the availability of potent antifungal agents, acute disseminated candidiasis remains a life-threatening disease in immunocompromised patients. Inhibition inflammasome activity confers resistance to polymicrobial and LPS-induced sepsis; however, signaling appears protect against C. albicans infection, so inhibitors are not clinically useful for candidiasis. Here we discovered that disruption GSDMD, known target key pyroptotic cell death mediator, paradoxically alleviated candidiasis,...
Abstract Backgrounds: Finite element analysis (FEA) is an important tool during the spinal biomechanical study. Irregular surfaces in FEA models directly reconstructed based on imaging data may increase computational burden and decrease credibility. Definitions of relative nucleus position its cross-sectional area ratio do not conform to a uniform standard FEA. Methods: To accuracy efficiency FEA, were measured from data. A model with smoothened was constructed using values, calibrated by...