Analysis of fat-soluble vitamins A, D, E levels in the serum of healthy children

• DOI: 10.3760/cma.j.issn.1674-635x.2016.06.005
• Publication Date: 2016-12-30
• Authors: Chunhua Jin; Xiaoyan Wang; Lili Zhang; Yue Zhang; Na Li; Jianhong Wang; Haitao Gao; Wenhong Song; Na Jin; Baojun Gao; Huaying Jiang; Hong Wang; Lijuan Mu; Lifang Sun; Xia Ren; Yingxin Fu; Chunmei Zheng
• Keywords: Subclinical infection; Fat-Soluble Vitamin; Vitamin E deficiency

Objective To investigate the serum levels of vitamin A, D, E in healthy children Beijing.

Methods We collected clinical data who had been living Beijing for more than six months. Their A and were measured by reverse phase high-performance liquid chromatography (HPLC) with fluorescence detection method; 25-hydroxy D [25-(OH)D] level was tandem mass spectrometry (HPLC-MS/MS).

Results A total 1 538 included. The average (0.30±0.07)mg/L; subclinical deficiency rate 5.2% (80/1 538), whom 70.0% (56/80) 3 years. Spearman' s correlation coefficients between 25-(OH)D, age 0.197, -0.420, -0.319, respectively.

Conclusions Serum may be mainly suspected state. Infants generally good nutritional status, while or insufficiency is prevalent school-age teenagers. Vitamin rare.

Key words: Child; Vitamin A; Vitamin E; 25-hydroxy D; Deficiency