Cloning and expression of Theileria parva T-complex 1 protein zeta subunit ortholog.
Theileria parva
Theileria
DOI:
10.5897/jcab.9000032
Publication Date:
2009-10-31
AUTHORS (2)
ABSTRACT
East coast fever (ECF) is a severe lymphoproliferative disease of cattle caused by the intracellular protozoan Theileria parva from family Apicomplexa. Gene homologs encoding antigens from other apicomplexan parasites constitute source vaccine candidate antigens. An ortholog zeta subunit T-complex protein 1 (TCP-1) which plays role in folding, assembly and transport was identified within the Theileria parva genome. The deduced amino acid sequence the T. parva ortholog has 55% identity 77% similarity to same number eukaryotes such as Danio rerio (zebra fish) man. this its own (Apicomplexa) slightly higher. The T. parvaTCP-1 zeta subunit gene cloned expressed in Escherichia coli and recombinant characterized.
Key words: T-complex protein, Theileria parva, apicomplexa, antigen.
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