Xiaoxi Sun

ORCID: 0000-0001-5011-2594
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About
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Research Areas
  • Sperm and Testicular Function
  • Reproductive System and Pregnancy
  • Reproductive Biology and Fertility

ShangHai JiAi Genetics & IVF Institute
2021

Obstetrics and Gynecology Hospital of Fudan University
2021

Objective This was a prospective study to investigate whether progesterone affects sperm activity by regulating the cyclic AMP-protein kinase A (cAMP-PKA) signalling pathway via α/β hydrolase domain-containing protein 2 (ABHD2). Methods Spermatozoa were collected from healthy and infertile men (with oligoasthenospermia or abnormal acrosome; n = 30/group). The expression of mutations in ABHD2 detected quantitative PCR, western blot, gene sequencing. presence all groups, cAMP PKA levels ELISA...

10.1177/0300060521999527 article EN cc-by-nc Journal of International Medical Research 2021-03-01
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