Xueqian Chen

ORCID: 0000-0001-5069-9663
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About
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Research Areas
  • Advanced biosensing and bioanalysis techniques
  • Biosensors and Analytical Detection
  • Polymer Surface Interaction Studies
  • Nanoplatforms for cancer theranostics
  • Carbon and Quantum Dots Applications
  • Phase Equilibria and Thermodynamics
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Molecular Sensors and Ion Detection
  • Nanocluster Synthesis and Applications
  • Luminescence and Fluorescent Materials
  • Quantum Dots Synthesis And Properties
  • Material Dynamics and Properties
  • Block Copolymer Self-Assembly
  • Marine Biology and Environmental Chemistry
  • Sulfur Compounds in Biology
  • Topology Optimization in Engineering
  • Force Microscopy Techniques and Applications
  • Surface Modification and Superhydrophobicity
  • Theoretical and Computational Physics
  • Electrochemical Analysis and Applications
  • Click Chemistry and Applications
  • Adhesion, Friction, and Surface Interactions
  • Advanced Fluorescence Microscopy Techniques
  • Microfluidic and Capillary Electrophoresis Applications
  • Physiological and biochemical adaptations

Zhengzhou University
2022-2024

Beijing University of Technology
2020-2024

East China University of Science and Technology
2011-2024

Qingdao Institute of Bioenergy and Bioprocess Technology
2024

Kunming University of Science and Technology
2024

Tsinghua University
2023-2024

Affiliated Hospital of North Sichuan Medical College
2024

Anhui Agricultural University
2020-2023

The Ohio State University
2023

State Key Laboratory of Chemical Engineering
2009-2023

In this paper, a facilely prepared electrochemiluminescence (ECL) biosensor was developed for Escherichia coli O157:H7 quantitative detection based on polydopamine (PDA) surface imprinted polymer (SIP) and nitrogen-doped graphene quantum dots (N-GQDs). N-GQDs with high yield of 43.2% were synthesized. The uniform PDA SIP film E. established successfully facile route. dopamine target bacteria electropolymerized directly the electrode. After removal template, can selectively recognize O157:H7....

10.1021/acsami.6b12455 article EN ACS Applied Materials & Interfaces 2017-01-18

Abstract Metamaterials composed of different geometrical primitives have properties. Corresponding to the fundamental forms line, plane, and surface, beam-, plate-, shell-based lattice metamaterials enjoy many advantages in aspects, respectively. To fully exploit each structural archetype, we propose a multilayer strategy topology optimization technique design metamaterial this study. Under frame strategy, space is enlarged diversified, freedom increased. Topology applied explore better...

10.1038/s41467-024-47089-8 article EN cc-by Nature Communications 2024-04-06

We discuss the performance of QD-based ECL sensors. critical sensing mechanisms review construction strategies QDs in systems. highlight advances and future trends

10.1039/c7tc05474b article EN Journal of Materials Chemistry C 2018-01-01

Early diagnosis of hepatic inflammation is the key to timely treatment and avoid worsening liver inflammation. Near-infrared fluorescence (NIRF) probes have high sensitivity but low spatial resolution in lesion imaging, while photoacoustic (PA) imaging has good location information. Therefore, development a NIRF/PA dual-modal probe integrated with feedback can achieve an accurate early Here, we report activatable (hCy-Tf-CA) for detection superoxide anion (O2·–) hCy-Tf-CA showed selectivity...

10.1021/acs.analchem.2c05476 article EN Analytical Chemistry 2023-01-16

Abstract In situ precise detection of bioactive molecules with high sensitivity and spatiotemporal resolution is essential for studying physiological events disease diagnosis. The utilization versatile fluorescent probes in fluorescence imaging offers a powerful tool vivo biomarkers closely associated pathological conditions. However, the dynamic behavior leading to rapid clearance small molecule from regions interest severely compromises their potential imaging. Notably, self‐immobilizing...

10.1002/smo.20240031 article EN cc-by Smart Molecules 2024-08-23

We rationally designed a leucine aminopeptidase (LAP) activated fluorogenic probe hCy-CA-LAP with high hepatocyte-targeting ability for accurate and sensitive imaging of DILI.

10.1039/d1sc04825b article EN cc-by-nc Chemical Science 2021-01-01

Abstract Glioblastoma (GBM) is the most aggressive primary brain tumor with poor prognosis and high recurrence rate. The presence of blood–brain barrier (BBB) prevents diagnostic therapeutic drugs from penetrating working in GBM. In traditional surgical treatment, it difficult to completely distinguish boundary between surrounding normal tissue, resulting incomplete resection tumor. Therefore, diagnosis treatment GBM are very challenging. Several molecular probes nanoprobes have been...

10.1002/viw.20220069 article EN cc-by View 2023-02-02

Novel fluorescence detection of dopamine based on nitrogen-doped graphene quantum dots and visible paper-based test strips.

10.1039/c7ay00028f article EN Analytical Methods 2017-01-01

A BN QDs-based ECL biosensor was established for the rapid detection of STEC in human blood, showing excellent selectivity, stability and high sensitivity.

10.1039/c8gc03010c article EN Green Chemistry 2018-01-01

10.1016/j.colsurfa.2021.127016 article EN Colloids and Surfaces A Physicochemical and Engineering Aspects 2021-06-15

Abstract With the rapid advancement of new energy industry, porous electrode materials and complex electrolytes have gained widespread usage. Electrolytes exhibit distinctive phase behavior when subjected to combined influence confined space electric fields. However, measurement prediction such encounter significant challenges. Consequently, numerous theoretical tools been employed establish models for equilibrium calculations. Nevertheless, current research in this field has notable...

10.1002/aic.18496 article EN AIChE Journal 2024-06-05

Electrochemiluminescence (ECL) of the luminol-dissolved O2 system has been applied in many fields, but role reactive oxygen species (ROS) potential-resolved ECL remains ambiguous due to complexity ROS production and difficulty detecting ROS. In this work, function potential-dependent luminol-O2 was investigated detail. Interestingly, four peaks were observed profiles, including a cathodic peak at −0.5 V (ECL-1), two anodic 0.45 (ECL-2) 1.3 (ECL-3), broad flat starting from 1.11 ending 0.35...

10.1021/acs.jpcc.4c03871 article EN The Journal of Physical Chemistry C 2024-07-30

Knowledge of the interaction between aptamer and protein is integral to design development aptamer-based biosensors. Nanoparticles functionalized with aptamers are commonly used in these kinds sensors. As such, studies into how number on nanoparticle surface influence both kinetics thermodynamics binding required. In this study, specific for interferon gamma (IFN-γ) were immobilized gold nanoparticles (AuNPs), effect coverage its target was investigated using fluorescence spectroscopy. The...

10.1021/acssensors.0c02212 article EN ACS Sensors 2020-12-09
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