A5005824436- Nanopore and Nanochannel Transport Studies
- Electrostatics and Colloid Interactions
- Spectroscopy and Quantum Chemical Studies
University of Oxford
2023-2025
Zwitterionic osmolytes are widely known to have a protein-protective effect against high salt concentration, but mechanistic picture of osmolyte function remains elusive. Here total scattering is used determine...
Cellular organisms regulate electrolyte composition in the cytosol to optimize intracellular molecular interactions at same time as balancing external osmotic pressure. While pressure can be tuned using multiple ionic, zwitterionic, and nonionic solutes, between proteins other macromolecules are sensitive precise of medium. Nonetheless, roles individual ions solutes mediating cellular remain relatively unexplored, standard buffer solutions used laboratory studies often contain only a few...