A5069600756- Biomedical Text Mining and Ontologies
- Semantic Web and Ontologies
- Genetics, Bioinformatics, and Biomedical Research
- Scientific Computing and Data Management
- Bioinformatics and Genomic Networks
- Artificial Intelligence in Healthcare
- Medical Image Segmentation Techniques
- Genomics and Rare Diseases
- Genomics and Phylogenetic Studies
- Digital Image Processing Techniques
- Biomedical and Engineering Education
- Gene expression and cancer classification
- Service-Oriented Architecture and Web Services
- Rough Sets and Fuzzy Logic
- Image Retrieval and Classification Techniques
- Logic, programming, and type systems
- Logic, Reasoning, and Knowledge
- Data Mining Algorithms and Applications
- Formal Methods in Verification
- Electronic Health Records Systems
- Bayesian Modeling and Causal Inference
- Polynomial and algebraic computation
- AI-based Problem Solving and Planning
- Information Retrieval and Search Behavior
- Cell Image Analysis Techniques
Universidad Politécnica de Madrid
2010-2021
Intel (United States)
2014
Harvard University
2005
Artificial Intelligence Research Institute
2005
Instituto de Salud Carlos III
2004
Universidad Complutense de Madrid
2001-2004
Rutgers, The State University of New Jersey
2003
Abstract: Over a decade ago, nanotechnologists began research on applications of nanomaterials for medicine. This has revealed wide range different challenges, as well many opportunities. Some these challenges are strongly related to informatics issues, dealing, instance, with the management and integration heterogeneous information, defining nomenclatures, taxonomies classifications various types nanomaterials, new modeling simulation techniques nanoparticles. Nanoinformatics recently...
In this report, the authors compare and contrast medical informatics (MI) bioinformatics (BI) provide a viewpoint on their complementarities potential for collaboration in various subfields. The MI BI along several dimensions, including: (1) historical development of disciplines, (2) scientific foundations, (3) data quality analysis, (4) integration knowledge databases, (5) tools to support practice, (6) methods research (signal processing, imaging vision, computational modeling, (7)...
Abstract In the vector space model for information retrieval, term vectors are pair‐wise orthogonal, that is, terms assumed to be independent. It is well known this assumption too restrictive. article, we present our work on an indexing and retrieval method that, based model, incorporates dependencies thus obtains semantically richer representations of documents. First, generate context co‐occurrence in same These used calculate We different techniques estimating among terms. also define...
Background and objective: Nanoparticles present properties that can be applied to a wide range of fields such as biomedicine, electronics or optics. The type depends on several characteristics, being some them related with the particle structure. A proper characterization nanoparticles is crucial since it could affect their applications. To characterize shape size, nanotechnologists employ Electron Microscopy (EM) obtain images perform measures over them. This task tedious, repetitive slow,...
Summary Objective: To outline the main issues related to impact of data generated by Human Genome Project on health information systems. A major challenge for medical informatics is identified, consisting adapting traditional systems new genetic-based diagnostic and therapeutic tools. Methods: Reviewing analysing different levels from an organisational complexity point view. model proposed explain interactions between informatics, bioinformatics molecular medicine. Results: We suggest a...
The rapid evolution of Internet technologies and the collaborative approaches that dominate field have stimulated development numerous bioinformatics resources. To address this new framework, several initiatives tried to organize these services In paper, we present BioInformatics Resource Inventory (BIRI), a approach for automatically discovering indexing available public resources using information extracted from scientific literature. index generated can be updated by adding additional...
Epidemiologists are reformulating their classical approaches to diseases by considering various issues associated "omics" areas and technologies. Traditional differences between epidemiology genetics include background, training, terminologies, study designs others. Public health increasingly looking forward using methodologies informatics tools, facilitated the Bioinformatics community, for managing genomic information. Our aim is describe which most important implications related with...
In this work, we describe the set of tools comprising Data Access Infrastructure within Advancing Clinic-genomic Trials on Cancer (ACGT), a R&D Project funded in part by European. This infrastructure aims at improving Post-genomic clinical trials providing seamless access to integrated clinical, genetic, and image databases. A data layer, based OGSA-DAI, has been developed order cope with syntactic heterogeneities The semantic problems present sources different nature are tackled two core...
Nanoinformatics is an emerging research field that uses informatics techniques to collect, process, store, and retrieve data, information, knowledge on nanoparticles, nanomaterials, nanodevices their potential applications in health care. In this paper, we have focused the solutions nanoinformatics can provide facilitate nanotoxicology research. For this, taken a computational approach automatically recognize extract nanotoxicology-related entities from scientific literature. The desired...
Summary Objectives: Biomedical ontologies have been very successful in structuring knowl edge for many different applications, receiving widespread praise their utility and potential. Yet, the role of computational scientific research, as opposed to knowledge management has not extensively discussed. We aim stimulate further discussion on advantages challenges presented by biomedical from a perspective. Methods: review various aspects going beyond practical successes, focus some key...
Summary Objectives: To propose a modification to current methodologies for clinical trials, improving data collection and cost-efficiency. describe system integrate distributed heterogeneous medical genetic databases information access, retrieval analysis of biomedical information. Methods: Data trials can be collected from remote, sources. In this scenario, we an ontology-based approach, with two basic operations: mapping unification. Mapping outputs the semantic model virtual repository...
Nanotechnology represents an area of particular promise and significant opportunity across multiple scientific disciplines. Ongoing nanotechnology research ranges from the characterization nanoparticles nanomaterials to analysis processing experimental data seeking correlations between their functionalities side effects. Due special properties, are suitable for cellular-level diagnostics therapy, offering numerous applications in medicine, e.g. development biomedical devices, tissue repair,...
Background Clinical Trials (CTs) are essential for bridging the gap between experimental research on new drugs and their clinical application. Just like CTs traditional biologics have helped accelerate translation of biomedical findings into medical practice, nanodrugs nanodevices could advance novel nanomaterials as agents diagnosis therapy. Although there is publicly available information about nanomedicine-related CTs, online archiving this carried out without adhering to criteria that...
This study presents the impact of carbon nanotubes (CNTs) on mitochondrial oxygen mass flux (Jm) under three experimental conditions. New results and a new methodology are reported for first time they based CNT Raman spectra star graph transform (spectral moments) perturbation theory. The measures Jm showed that no tested family can inhibit consumption profiles mitochondria. best model prediction other CNTs was provided by random forest using eight features, obtaining test R-squared (R²)...